High anxiety is associated with an increased risk of death in an older tri-ethnic population

Ostir, Glenn V.; Goodwin, James S.

doi:10.1016/j.jclinepi.2005.10.008

Cited by 39 publications

(24 citation statements)

References 37 publications

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“…There is a widespread belief that heart disorders are associated with psychological stress, and particularly with depression and anxiety (28). In the present study, the heart disease was associated only with anxiety.…”

Section: Variablesupporting

confidence: 42%

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Clustering of psychiatric and somatic illnesses in the general population: multimorbidity and socioeconomic correlates

Andrade

Viana

Andreoni

et al. 2010

Braz J Med Biol Res

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The distribution of psychiatric disorders and of chronic medical illnesses was studied in a population-based sample to determine whether these conditions co-occur in the same individual. A representative sample (N = 1464) of adults living in households was assessed by the Composite International Diagnostic Interview, version 1.1, as part of the São Paulo Epidemiologic Catchment Area Study. The association of sociodemographic variables and psychological symptoms regarding medical illness multimorbidity (8 lifetime somatic conditions) and psychiatric multimorbidity (15 lifetime psychiatric disorders) was determined by negative binomial regression. A total of 1785 chronic medical conditions and 1163 psychiatric conditions were detected in the population concentrated in 34.1 and 20% of respondents, respectively. Subjects reporting more psychiatric disorders had more medical illnesses. Characteristics such as age range (35-59 years, risk ratio (RR) = 1.3, and more than 60 years, RR = 1.7), being separated (RR = 1.2), being a student (protective effect, RR = 0.7), being of low educational level (RR = 1.2) and being psychologically distressed (RR = 1.1) were determinants of medical conditions. Age (35-59 years, RR = 1.2, and more than 60 years, RR = 0.5), being retired (RR = 2.5), and being psychologically distressed (females, RR = 1.5, and males, RR = 1.4) were determinants of psychiatric disorders. In conclusion, psychological distress and some sociodemographic features such as age, marital status, occupational status, educational level, and gender are associated with psychiatric and medical multimorbidity. The distribution of both types of morbidity suggests the need of integrating mental health into general clinical settings.

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Section: Variablesupporting

confidence: 42%

“…There is some evidence linking depression and anxiety to hypertension (28). One possible mechanism could be the presence of increased levels of circulating catecholamine in people with anxiety or depression (29).…”

Section: Variablementioning

confidence: 99%

Clustering of psychiatric and somatic illnesses in the general population: multimorbidity and socioeconomic correlates

Andrade

Viana

Andreoni

et al. 2010

Braz J Med Biol Res

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“…Also common in 10–70% of dementia sufferers are behavioral and psychiatric symptoms of dementia (BPSDs) such as agitation, aggression (physical and verbal), and psychosis 2 . Late‐life psychiatric disturbances result in a lower quality of life; an increase in disability rates; and a risk of dementia, placement in long‐term care, and cognitive decline as well as a risk of extrapyramidal symptoms and mortality, which may include suicide 5 , 5 , 5 , 5 …”

Section: Late‐life Psychiatric Disturbancesmentioning

confidence: 99%

The Critical Role of Clinical Pharmacology in Geriatric Psychopharmacology

Pollock

Forsyth

Bies

2008

Clin Pharmacol Ther

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There is limited geriatrics‐oriented clinical pharmacological information available to guide pharmacotherapy in late‐life psychiatric disorders. In this paper, we review available data on interindividual differences in drug exposure and central nervous system functioning, amplified by drug–drug interactions in the elderly, that may contribute to variable responses to treatment and significant adverse drug effects. The inclusion of greater numbers of elderly persons in clinical trials and the vigorous application of clinical pharmacologic methodology (i.e., pharmacoepidemiology, population pharmacokinetic modeling, and pharmacogenetics) will be critical for improving safety and personalization of drug and dose selection for elderly patients. Clinical Pharmacology & Therapeutics (2008); 85, 1, 89–93 doi:

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“…At an individual level, anxiety symptoms and disorders have been found to be associated with increased sleep disturbance (Brenes et al, 2009), intake of anxiety related medication (Gonç alves, Pachana, & Byrne, 2011), disability (Brenes et al, 2005), mortality (Ostir & Goodwin, 2006), and decreased cognitive functioning (Beaudreau & O'Hara, 2009;Mantella et al, 2007). At a societal level, late-life anxiety was related to increased use of health services, namely longer appointments with physicians (Stanley, Roberts, Bourland, & Novy, 2001), and inability to perform daily functions (Trollor, Anderson, Sachdev, Brodaty, & Andrews, 2007).…”

Section: Introductionmentioning

confidence: 99%

Interventions for generalized anxiety disorder in older adults: Systematic review and meta-analysis

Gonçalves

Byrne

2012

Journal of Anxiety Disorders

165

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High anxiety is associated with an increased risk of death in an older tri-ethnic population

Abstract: There is a high prevalence of anxiety in late life. Our results indicate an association between anxiety and increased risk of death in persons aged 75 and older.

Cited by 39 publications

References 37 publications

Clustering of psychiatric and somatic illnesses in the general population: multimorbidity and socioeconomic correlates

Clustering of psychiatric and somatic illnesses in the general population: multimorbidity and socioeconomic correlates

The Critical Role of Clinical Pharmacology in Geriatric Psychopharmacology

Interventions for generalized anxiety disorder in older adults: Systematic review and meta-analysis

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