Hidradenitis suppurativa among patients with HIV: investigating patient and disease characteristics and misdiagnosis

Bui, Helen; Skiba, P.N.; Breskin, Alexander; Sayed, Christopher

doi:10.1111/bjd.20591

Cited by 3 publications

(6 citation statements)

References 9 publications

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“…Regarding the relationship between HIV and the increased rates and severity of chronic inflammatory skin disorders, such as HS, to date it remains poorly understood. Being an immunodeficiency syndrome, HIV could promote the onset and progression of HS owing to immune dysregulation [ 37 ]. Bui et al evaluated in their study a population of patients affected by HS and HIV, assessing the rates of HS misdiagnosis in the HIV + community [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

“…Being an immunodeficiency syndrome, HIV could promote the onset and progression of HS owing to immune dysregulation [ 37 ]. Bui et al evaluated in their study a population of patients affected by HS and HIV, assessing the rates of HS misdiagnosis in the HIV + community [ 37 ]. Data from 63 adults revealed that the onset of HS in patients with HS and HIV was later than in those living with HS only (2nd–3rd decade of life).…”

Section: Discussionmentioning

confidence: 99%

“…Data from 63 adults revealed that the onset of HS in patients with HS and HIV was later than in those living with HS only (2nd–3rd decade of life). HIV diagnosis was made before HS onset in 63.8% of subjects [ 37 ]. A predisposing effect of HIV infection in the development of HS has been suggested considering the late age of HS onset on one side and the high rate of HS onset after initial HIV diagnosis on the other [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

“…HIV diagnosis was made before HS onset in 63.8% of subjects [ 37 ]. A predisposing effect of HIV infection in the development of HS has been suggested considering the late age of HS onset on one side and the high rate of HS onset after initial HIV diagnosis on the other [ 37 ]. Indeed, Deng et al found a six-fold higher rate of HS diagnosis in patients with HIV compared with those without HIV [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

“…It could seem paradoxical that severe skin manifestations are more frequent in HIV-patients than the general population [ 37 ]. However, it is common opinion that the immune dysregulation caused by both pathologies could represent the right interpretation [ 36 , 37 , 51 ].…”

Section: Discussionmentioning

confidence: 99%

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Hidradenitis Suppurativa in Patients with HIV: A Scoping Review

et al. 2022

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Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease of the apocrine glands. Bibliographic search revealed few studies concerning the association between HS and human immunodeficiency virus (HIV). To assess this link, we performed a systematic review of the current knowledge through a careful analysis of the relevant and authoritative medical literature in the field. Results showed that people with HIV are particularly susceptible to developing HS with the characteristic involvement of atypical sites, such as face or thighs, due to HIV-related immunosuppression. Based on the pathogenesis of both conditions and according to our review, we suggest that HIV screening should be routinely performed in suspected cases while monitoring and integrated approach in management are mandatory in the management of HIV-positive patients with HS.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%