Hidradenitis Suppurativa; Abscess of the Apocrine Sweat Glands

Brunsting, Henry A.

doi:10.1001/archderm.1939.01480190111010

Cited by 97 publications

(16 citation statements)

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“…25 The histology was defined in 1939 by Brunsting, who suggested that the inciting event was luminal obstruction of the apocrine glands. 26 Apocrine glands are compound sweat glands located in the dermis of the axilla, inguinal, perineal, and perianal regions of the body. Each gland is composed of a coiled secretory unit that drains through a long excretory duct into a hair follicle.…”

Section: Pathogenesis Of Hsmentioning

confidence: 99%

Painful Hidradenitis Suppurativa

Smith

Chao

Teitelbaum

2010

The Clinical Journal of Pain

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Hidradenitis suppurativa (HS) is a chronically relapsing skin disorder characterized by recurring inflammatory lesion in hair and apocrine gland-bearing skin creases in the axilla; groin or perineum, buttocks, and/or breast. HS may lead to painful eruptions and malodorous discharge significantly detracting from quality of life. HS causes a high degree of morbidity with the highest scores obtained for the level of pain caused by the disease. The majority of patients rated their pain on a Numerical Rating Scale-11 ranging from 4/10 to 10/10 and described it at various times as hot, burning, pressure, stretching, cutting, sharp, taut, splitting, gnawing, pressing, sore, throbbing, and aching. Despite the severe pain associated with this disease, HS has been essentially ignored in the pain medicine literature. It is hoped that greater understanding of the diagnosis, pathophysiology, and potential treatment options available for patients with HS, may help put pain specialists in a better position to contribute to the overall care of patients with significantly painful HS. This article reviews HS and pain. Potential mechanisms of modulating nociceptive processes in the skin are presented. A greater understanding of the diagnosis, pathophysiology, and potential treatment options for HS patients may help providers to be better able to contribute to care of patients with painful hidradenitis suppurativa.

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Section: Pathogenesis Of Hsmentioning

confidence: 99%

Painful Hidradenitis Suppurativa

Smith

Chao

Teitelbaum

2010

The Clinical Journal of Pain

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“…[9][10][11][12] Clinical manifestations and response to treatment, however, remain very different, e.g., acne prominently involves the sebaceous apparatus while HS does not. 13,14 The continued publication of case reports of the follicular occlusion triad also suggest that co-occurrence is rare.…”

Section: Nosologymentioning

confidence: 99%

Hidradenitis Suppurativa

Jemec

2002

JCMS

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“…4 However, inflamed apocrine glands are found only when in proximity to other inflamed structures. [5][6][7] The true etiology of HS is unknown. Current thought is that HS is a disorder of terminal follicular epithelium within apocrine gland-bearing skin.…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of Hidradenitis Suppurativa of the Nipple–Areolar Complex

Mofid

Goldberg

et al. 2004

Annals of Plastic Surgery

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Involvement of the nipple-areolar complex is an infrequent area of distribution of hidradenitis suppurativa. The difficulty of this particular distribution has been encountered in the past and resulted in bilateral mastectomies. The authors describe successful treatment of a patient with hidradenitis suppurativa of the breasts and nipple-areolar complexes using breast-conserving measures. Normal breast contour was preserved and overall cosmetic result was good.

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Hidradenitis Suppurativa; Abscess of the Apocrine Sweat Glands

Cited by 97 publications

References 4 publications

Painful Hidradenitis Suppurativa

Painful Hidradenitis Suppurativa

Hidradenitis Suppurativa

Surgical Management of Hidradenitis Suppurativa of the Nipple–Areolar Complex

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