Heterogeneous Catalysis and Solid Catalysts, 3. Industrial Applications

Catalytic Hydrogenation of CO2 to Methanol over Cu/MgO Catalysts in a Semi-Continuous Reactor

“…The bench-scale semi-continuous tank reactor was adapted according to state-of-theart reactor configurations for industrial methanol synthesis [10]. As opposed to syngasbased industrial methanol synthesis, pure CO 2 was used as carbon source in this study.…”

Catalytic Hydrogenation of CO2 to Methanol over Cu/MgO Catalysts in a Semi-Continuous Reactor

“…The bench-scale semi-continuous tank reactor was adapted according to state-of-theart reactor configurations for industrial methanol synthesis [10]. As opposed to syngasbased industrial methanol synthesis, pure CO 2 was used as carbon source in this study.…”

Scalable direct N-methylation of drug-like amines using 12CO2/13CO2 by simple inorganic base catalysis

“…Several other prominent features are also notable: (i) the substitution position at the anilinic phenyl ring, ortho-, meta-or para-, only has a small impact onto the reaction (2-4); (ii) both electron-donating and electron-withdrawing groups are well tolerated, including chloro, bromo, fluoro, methyl, methoxyl, cyano, ester, cabonyl, amide and nitro (4-13); (iii) steric hindrance in diisopropylamine (27) or substrates with the N-methyl group for derivatives of aniline/ benzyl amine replaced by ethyl, isopropyl, cyclohexyl, benzyl, and cyclopropyl group (14-17, 24-26) is also well tolerated; (iv) cyclic amine (18) and diphenyl amine (19) are also suitable substrates; and (v) chemoselective functionalization of substrates with multiple nucleophilic sites is a classical challenge in organic synthesis [40]. Surprisingly, the present simple inorganic base catalysis allows for selective N-monomethylation of anilinic NAH in the presence of another nucleophilic site, boc-protected NH (20) or hydroxyl group (21), in the same substrate without any condition optimization; (vi) selective methylation of bicyclic aliphatic amine was also successfully achieved in the presence of ketone (28).…”

Quantitative analysis of CO 2 emissions reduction potential of alternative light olefins production processes

“…15 CO hydrogenation via the FT reaction produces a hydrocarbon mixture with an Anderson-Schulz-Flory (ASF) distribution, (eqn (1)) and methane formation cannot be avoided. 19 Selectivity to C 2 -C 3 hydrocarbons is maximized for a chain growth probability α between 0.5 and 0.7, yet the selectivity to CH 4 is also high for that α range, i.e., 30-50%.…”

Catalytic Hydrogenation of CO2 to Methanol over Cu/MgO Catalysts in a Semi-Continuous Reactor

“…The bench-scale semi-continuous tank reactor was adapted according to state-of-theart reactor configurations for industrial methanol synthesis [10]. As opposed to syngasbased industrial methanol synthesis, pure CO 2 was used as carbon source in this study.…”

Scalable direct N-methylation of drug-like amines using 12CO2/13CO2 by simple inorganic base catalysis

“…Several other prominent features are also notable: (i) the substitution position at the anilinic phenyl ring, ortho-, meta-or para-, only has a small impact onto the reaction (2-4); (ii) both electron-donating and electron-withdrawing groups are well tolerated, including chloro, bromo, fluoro, methyl, methoxyl, cyano, ester, cabonyl, amide and nitro (4-13); (iii) steric hindrance in diisopropylamine (27) or substrates with the N-methyl group for derivatives of aniline/ benzyl amine replaced by ethyl, isopropyl, cyclohexyl, benzyl, and cyclopropyl group (14-17, 24-26) is also well tolerated; (iv) cyclic amine (18) and diphenyl amine (19) are also suitable substrates; and (v) chemoselective functionalization of substrates with multiple nucleophilic sites is a classical challenge in organic synthesis [40]. Surprisingly, the present simple inorganic base catalysis allows for selective N-monomethylation of anilinic NAH in the presence of another nucleophilic site, boc-protected NH (20) or hydroxyl group (21), in the same substrate without any condition optimization; (vi) selective methylation of bicyclic aliphatic amine was also successfully achieved in the presence of ketone (28).…”

Quantitative analysis of CO 2 emissions reduction potential of alternative light olefins production processes

“…15 CO hydrogenation via the FT reaction produces a hydrocarbon mixture with an Anderson-Schulz-Flory (ASF) distribution, (eqn (1)) and methane formation cannot be avoided. 19 Selectivity to C 2 -C 3 hydrocarbons is maximized for a chain growth probability α between 0.5 and 0.7, yet the selectivity to CH 4 is also high for that α range, i.e., 30-50%.…”

Catalytic Hydrogenation of CO2 to Methanol over Cu/MgO Catalysts in a Semi-Continuous Reactor

“…The bench-scale semi-continuous tank reactor was adapted according to state-of-theart reactor configurations for industrial methanol synthesis [10]. As opposed to syngasbased industrial methanol synthesis, pure CO 2 was used as carbon source in this study.…”

Scalable direct N-methylation of drug-like amines using 12CO2/13CO2 by simple inorganic base catalysis

“…Several other prominent features are also notable: (i) the substitution position at the anilinic phenyl ring, ortho-, meta-or para-, only has a small impact onto the reaction (2-4); (ii) both electron-donating and electron-withdrawing groups are well tolerated, including chloro, bromo, fluoro, methyl, methoxyl, cyano, ester, cabonyl, amide and nitro (4-13); (iii) steric hindrance in diisopropylamine (27) or substrates with the N-methyl group for derivatives of aniline/ benzyl amine replaced by ethyl, isopropyl, cyclohexyl, benzyl, and cyclopropyl group (14-17, 24-26) is also well tolerated; (iv) cyclic amine (18) and diphenyl amine (19) are also suitable substrates; and (v) chemoselective functionalization of substrates with multiple nucleophilic sites is a classical challenge in organic synthesis [40]. Surprisingly, the present simple inorganic base catalysis allows for selective N-monomethylation of anilinic NAH in the presence of another nucleophilic site, boc-protected NH (20) or hydroxyl group (21), in the same substrate without any condition optimization; (vi) selective methylation of bicyclic aliphatic amine was also successfully achieved in the presence of ketone (28).…”

Quantitative analysis of CO 2 emissions reduction potential of alternative light olefins production processes

“…15 CO hydrogenation via the FT reaction produces a hydrocarbon mixture with an Anderson-Schulz-Flory (ASF) distribution, (eqn (1)) and methane formation cannot be avoided. 19 Selectivity to C 2 -C 3 hydrocarbons is maximized for a chain growth probability α between 0.5 and 0.7, yet the selectivity to CH 4 is also high for that α range, i.e., 30-50%.…”