1993
DOI: 10.1590/s0036-46651993000300011 View full text |Buy / Rent full text
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Abstract: The objective of the present study was to estimate the prevalence of herpes simplex virus type 2 (HSV 2) antibodies in child bearing women of 2 Brazilian populations with different socioeconomic status and to determine the risk of neonatal HSV exposure by means of maternal cultures at the onset of labor. The study was conducted at 2 hospitals: A, serving very low income patients and B, serving middle socioeconomic class. 173 participants from group A and 127 from B answered a questionnaire which showed that th… Show more

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“…History of genital herpes was obtained from 21.8% of the HSV-2 positive subjects, which indicates that only a low proportion of the patients were aware of the HSV-2 infection. This finding is in accordance with other reports (Weinberg et al 1993, Russel et al 2001, van Benthem et al 2001, confirming that clinical information greatly underestimates the prevalence of HSV-2 disease and underscores the importance of teaching these patients how to identify the episodes of active genital herpes (Langenberg et al 1989, Weinberg et al 1993) and counseling them to seek health care for genital signs and symptoms. The potential role of HSV-2 infection in facilitating HIV transmission highlights the need for including anti-HSV-2 testing and therapy in the management of HIV positive patients, especially for reducing the risk of transmission of HIV through herpetic lesions (Suligoi et al 2002).…”
Section: Discussionsupporting
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“…History of genital herpes was obtained from 21.8% of the HSV-2 positive subjects, which indicates that only a low proportion of the patients were aware of the HSV-2 infection. This finding is in accordance with other reports (Weinberg et al 1993, Russel et al 2001, van Benthem et al 2001, confirming that clinical information greatly underestimates the prevalence of HSV-2 disease and underscores the importance of teaching these patients how to identify the episodes of active genital herpes (Langenberg et al 1989, Weinberg et al 1993) and counseling them to seek health care for genital signs and symptoms. The potential role of HSV-2 infection in facilitating HIV transmission highlights the need for including anti-HSV-2 testing and therapy in the management of HIV positive patients, especially for reducing the risk of transmission of HIV through herpetic lesions (Suligoi et al 2002).…”
Section: Discussionsupporting
“…The HSV-2 seroprevalence of 52% observed in our study population is higher than that reported in antenatal clinic attenders (29%; mean age: 24.9 years) and blood donors (26%; mean age: 37.4 years) in Brazil (Weinberg et al 1993, Lupi 1995, 1998, Cowan et al 2003, supporting the strong association between the two infections. According to Russel et al (2001), the higher rate of HSV-2 seen in HIV-antibody positive subjects may indicate that individuals who are infected by HSV are more likely to acquire HIV infection, and vice-versa.…”
Section: Discussionsupporting
“…A total of 476 subjects were in the low and 590 in the middle socioeconomic class. Since few subjects (23) were in the high socioeconomic stratum, they were grouped together with those of the middle socioeconomic class for analysis purposes. As forethnicity, 51.5% were caucasians, 37.9% were mixed 10.2% were black and 0.4% were Asian.…”
Section: Resultsmentioning
“…A população estudada caracterizou-se por apresentar baixo poder aquisitivo, sendo epidemiologicamente mais predisposta à infecção pelos HSV-2 26 . Em 1993, Weinberg et al 4 avaliaram a freqüência de soropositividade contra os HSV em parturientes de São Paulo. Considerando populações de alto e baixo nível socioeconômico, a positividade foi detectada em 86% e 92% dos casos, respectivamente.…”
Section: Discussionunclassified
“…Por sua vez, o HSV-2 é responsável por até 90% das lesões genitais e pode estar presente em até 10% das lesões orolabiais 3 . Em estudo epidemiológico no qual se avaliou a soropositividade do HSV-2 em gestantes de diferentes classes sociais, Weinberg et al 4 encontraram 31% de exames positivos entre gestantes de elevado nível sócio-econômico e 46% naquelas de baixo poder aquisitivo. No entanto, esta diferença não foi significante.…”
Section: Introductionunclassified