Herpes simplex infection complicating Darier's disease. Caused by type 1 herpesvirus hominis

Recurrent Kaposi's varicelliform eruption in Darier's disease

“…This patient demonstrated the classical picture of hyperkeratosis foUicularis and presented many of the features previously recorded when Kaposi's varicelliform eruption is superimposed on this disease. The primary infection with herpes simplex virus, confirmed by virus isolation and serology, was accompanied by a profound constitutional disturbance as was seen in the patients observed by von Weiss and his colleagues (1965) and by Izumi & Goldschmidt (1970). The dramatic response to cytosine arabinoside confirmed the reports of the beneficial effect of this compound in herpes simplex infections (Chow, Foerster & Hryniuk, 1970;Juel-Jensen, 1970).…”

Eczema Herpeticum in a Man of 68

“…Most cases occur in the presence of atopic eczema and in children, but it may occur with other chronic dermatitis [McNair Scott, 1971], and in atopic subjects without active skin disease. Patients with Darier's disease [Izumi and Goldschmidt, 1970], pemphigus foliaceus [Silverstein and Burnett, 1967], ichthyosiform erythroderma [Fitzgerald and Booker, 1951] and dominant ichthyosis vulgaris [ Verhov et al, 1972] may also be affected. There are many points of particular interest in this patient.…”

Eczema vaccinatum in a family with Darier's disease

“…It has been reported that the lesions of Darier's disease improved on the virus infected areas after eczema herpeticum (Bleiberg & Kiosk, 1951;Hitselberger & Burns, 1961;von Weiss et al, 1965;Doeglas& Moolhuysen, 1969;Izumi& Goldsmith, 1970) and eczema vaccinatum (Gerstein & Shelley,i960). This interesting phenomenon was observed also in the present patients.…”