2009
DOI: 10.1155/2009/717183
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Abstract: Introduction. Herpes simplex esophagitis is well recognized in immunosuppressed subjects, but it is infrequent in immunocompetent patients. We present a case of HSE in a 53-year-old healthy man. Materials and Methods. The patient was admitted with dysphagia, odynophagia, and retrosternal chest pain. An esophagogastroduodenoscopy revealed minute erosive area in distal esophagus and biopsies confirmed esophagitis and findings characteristic of Herpes Simplex Virus infection. Results. The patients was treated wit… Show more

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Cited by 17 publications
(38 citation statements)
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“…HSV-1 esophagitis diagnosis is based on the endoscopic findings confirmed by histopathological examination of the esophagitis lesions (10,11,12,14,19). The place of the virological diagnosis in an HSV-1 esophagitis diagnosis remains unclear.…”
Section: Discussionmentioning
confidence: 99%
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“…HSV-1 esophagitis diagnosis is based on the endoscopic findings confirmed by histopathological examination of the esophagitis lesions (10,11,12,14,19). The place of the virological diagnosis in an HSV-1 esophagitis diagnosis remains unclear.…”
Section: Discussionmentioning
confidence: 99%
“…HSV-1 esophagitis is well documented in immunocompromised patients, whereas this clinical entity is rare in immunocompetent patients (2,4,5,9). HSV-1 esophagitis may represent a primary infection in particular in the immunocompetent host but is commonly due to a reactivation of a latent infection in the immunocompromised host (7).Friable mucosa, numerous ulcers, and whitish exudates commonly involving the distal or the midesophagus are classical endoscopic aspects in HSV-1 esophagitis (10,11,14,19). These findings require confirmation by histological examination completed with immunohistochemical staining of the biopsy specimens from the ulcer edges, which still remains the "gold standard" for HSV-1 esophagitis diagnosis (13,14,19).…”
mentioning
confidence: 99%
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“…It usually presents with the development of unexplained acute and intense odynophagia, dysphagia, chest pain, fever, and, in 23% of all the cases, respiratory symptoms (cough) are present (2). Prodromal symptoms are often nonspecific and associated with malaise.…”
Section: Introductionmentioning
confidence: 99%
“…The initial clinical suspicion allows for a prompt diagnosis and the establishment of the correct therapeutic measures to prevent an insidious course of the disease and its complications (2,3).…”
Section: Introductionmentioning
confidence: 99%