Herpes gestationis persisting for 12 years post partum

Pemphigoid Gestationis: Clinical and Laboratory Evaluation

“…One patient received azathioprine due to the chronic course of her disease, and the lesions lasted for over one year. Prolonged courses of PG,11–14 as well as transformation of the disease into BP 15 have been described. Many attempts to differentiate chronic PG from BP have been made: PG is associated with HLA DR3 and DR4, while BP is associated with HLA-DQ3 2,16,17.…”

Dermatoses Específicas da Gravidez

“…3 PG é, por definição, considerado crónico quando a dermatose tem duração superior a seis meses no período pós-parto, o que foi reportado em cerca de 20 casos. [5][6][7][8] O PG pode recorrer em gestações subsequentes ou com a toma de anticonceptivos orais e menstruação. 9 A recorrência tipicamente ocorre em dias a semanas após iniciar o anticonceptivo oral e desaparece após a sua suspensão.…”

Severe persistent pemphigoid gestationis: long-term remission with rituximab

“…The incidence of PG is estimated at between 1 in 10 000 and 1 in 50 000 pregnancies 1 . In most cases PG affects women in the sixth to ninth gestational month and usually resolve spontaneously within weeks to months after delivery; however, flares can occur at or immediately after delivery and very uncommonly the disease persists for months or even years postpartum 2–6 . Corticosteroids are the mainstay of therapy, but administration of high doses for a long period of time has considerable risk of severe irreversible side‐effects.…”