1973
DOI: 10.1001/archderm.107.6.888
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Herpes gestationis. Histology and ultrastructure

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Cited by 23 publications
(10 citation statements)
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“…Immunopathological and light and electron microscopic studies on patients with herpes gestationis show that there is a close relationship between this condition and bullous pemphigoid. This study on eleven patients supports previous reports (Provost & Tomasi, 1973;Bushkell et al, 1974;Schaumburg-Lever et al, 1973;Hertz et al, 1976;Yaoita et al, 1976;Honigsmann et al, 1976;Carruthers £/a/., 1977).…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…Immunopathological and light and electron microscopic studies on patients with herpes gestationis show that there is a close relationship between this condition and bullous pemphigoid. This study on eleven patients supports previous reports (Provost & Tomasi, 1973;Bushkell et al, 1974;Schaumburg-Lever et al, 1973;Hertz et al, 1976;Yaoita et al, 1976;Honigsmann et al, 1976;Carruthers £/a/., 1977).…”
Section: Discussionsupporting
confidence: 92%
“…The ultrastructural changes seen in this study correspond to those reported (Schaumburg-Lever et al, 1973;Yaoita et al, 1976). The main finding is a necrosis of basal cells.…”
Section: Discussionsupporting
confidence: 88%
“…Herpes gestationis (HG) is an auloimmune bullous disease of pregnancy and postpartum period (14), clinically and imnuinologically reminiscent of BP. lmmunopathologically, it is characterized by in vivo bound IgG and C3 at the BMZ and by circulating HG factor (15), which was later shown lo be complement fixing anli-BMZ antibodies (16).…”
Section: Introductionmentioning
confidence: 99%
“…The separation of the basal cells from the basal lamina takes place as a result of tearing and subsequent disappearance of the anchoring filaments. The half desmosomes dis-appear, the plasma membrane of the basal cells is damaged, and their cytoplasm shows signs of degeneration (9,10,11). The intercellular space between the basal cells is filled with edema.…”
Section: Pathomorphological Findingsmentioning
confidence: 99%
“…The intercellular space between the basal cells is filled with edema. In inflamed "infiltrate-rich" lesions a pronounced cellular infiltrate of eosinophils and histiocytes is the earliest finding (11). Subsequently, the basal lamina develops small discontinuities, which progress to fragmentation and disappearance of large portion of basal lamina even before a bulla has formed.…”
Section: Pathomorphological Findingsmentioning
confidence: 99%