Hepatitis C virus infection in Thai patients with oral lichen planus

Klanrit, Poramate; Thongprasom, Kobkan; Rojanawatsirivej, Somsri; Theamboonlers, Apiradee; Poovorawan, Yong

doi:10.1034/j.1601-0825.2003.00955.x

Cited by 39 publications

(46 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first report of a possible relation between HCV and OLP was established in 1991 by Mokin et al, [15]. In the present study all the patients were found to be seronegative to anti HCV antibody thus contradicting the report of an association between OLP and HCV.…”

Section: Discussioncontrasting

confidence: 56%

See 1 more Smart Citation

Oral Lichen Planus as an Extra–hepatic Manifestation of Viral Hepatitis–Evaluation in Indian Subpopulation

Kumar

Jois²,

Hallikerimath³

et al. 2013

JCDR

View full text Add to dashboard Cite

Background: Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes Chronic Liver Disease (CLD). Hepatitis virus B and C (HBV and HCV) have known to be important causative agents of CLD and can be prevalent in asymptomatic carriers that can make them difficult to identify. Off late, the association of viral hepatitis with OLP has been a subject of controversy due to conflicting reports. Indian studies on this regard are sparse to evaluate the same. Association between the hepatitis virus and OLP, if present and established, can be of great help to format a protocol for identifying carrier states of viral hepatitis due to HBV and HCV.Methodology: Forty five cases of clinically and histologically confirmed OLP were subjected to a serological screening of hepatitis B and C viruses by detection of hepatitis B surface antigen and anti-hepatitis C virus antibodies.Results: None of OLP cases were seropositive for the hepatitis viruses. Conclusion:We could not demonstrate any association between OLP and viral hepatitis. This could be attributed to lower prevalence of hepatitis viruses compared to the countries hyper endemic for these viruses or genotypic variation of the viruses or other etiological factors contributing for the present group of patients.

show abstract

Section: Discussioncontrasting

confidence: 56%

“…Till date there have been many published reports which have proposed the possible association between OLP and chronic liver disease such as that with primary biliary cirrhosis and with chronic active hepatitis [15].…”

Section: Discussionmentioning

confidence: 99%

Oral Lichen Planus as an Extra–hepatic Manifestation of Viral Hepatitis–Evaluation in Indian Subpopulation

Kumar

Jois²,

Hallikerimath³

et al. 2013

JCDR

View full text Add to dashboard Cite

show abstract

“…As they point out, OLP has been associated with a number of systemic disorders, generally of autoimmune origin (myasthenia gravis, Sjögren's syndrome, ulcerative colitis, psoriasis, celiac disease, some liver diseases, thymoma, and lupus erythematosus); however, only in a few conditions has this link been confirmed. [2][3][4][5][6] For example, the correlation between chronic hepatitis C virus (HCV) infection and OLP would be one of these, even if many contrasting results have been published, [7][8][9][10][11][12][13][14] and the partial dependency on geographic factors as well as genetic differences has been focused. 15,16 Furthermore, autoimmune conditions, such as systemic lupus erythematosus, rheumatoid arthritis, and celiac disease have also been simply found to be associated with autoimmune thyroid diseases, 17 but without great and definitive evidence.…”

Section: Association Of Oral Lichen Planus With Thyroid Disease In a mentioning

confidence: 99%

Association of oral lichen planus with thyroid disease in a Finnish population: A retrospective case-control study: “A different finding from a Mediterranean area”

Compilato¹,

Paderni²,

Fede³

et al. 2011

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

View full text Add to dashboard Cite

“…[15] have demonstrated that HCV infects keratinocytes from cutaneous LP lesions and that the viral RNA is translated in these cells as demonstrated by the HCV incorporated in the skin biopsies. Klanrit et al [16] showed a small but significant percentage of HCV infected patients with OLP. The study of Harman et al [11] supported the view that the consistency of HCV and OLP is probably more than coincidental and they recommend that it is appropriate to screen all patients with LP for HCV infection.…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report

Sachdeva¹,

Rout²,

Patnaik³

et al. 2017

IJBECS

View full text Add to dashboard Cite

Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. LP patients have about a fivefold higher risk than the controls of being HCV seropositive, with geographic variability, being most prevalent in the region of Japan, Mediterranean countries and the USA. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus. Also, the evolution of oral lesions is often fluctuating, with repeated periods of relapse according to the degree of liver function decompensation. Herewith, a case of oral lichen planus in a female patient is reported, which on investigation revealed hepatitis C antibodies.

show abstract

Hepatitis C virus infection in Thai patients with oral lichen planus

Abstract: The present study reports a small, but statistically significant high prevalence of HCV infection among patients with OLP, although the underlying mechanism still remains unknown.

Cited by 39 publications

References 52 publications

Oral Lichen Planus as an Extra–hepatic Manifestation of Viral Hepatitis–Evaluation in Indian Subpopulation

Oral Lichen Planus as an Extra–hepatic Manifestation of Viral Hepatitis–Evaluation in Indian Subpopulation

Association of oral lichen planus with thyroid disease in a Finnish population: A retrospective case-control study: “A different finding from a Mediterranean area”

Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report

Contact Info

Product

Resources

About