2008
DOI: 10.1186/1471-2180-8-11
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Abstract: Background: Lamivudine is an oral nucleoside analogue widely used for the treatment of chronic hepatitis B. The main limitation of lamivudine use is the selection of resistant mutations that increases with time of utilization. Hepatitis B virus (HBV) isolates have been classified into eight genotypes (A to H) with distinct geographical distributions. HBV genotypes may also influence pathogenic properties and therapeutic features. Here, we analyzed the HBV genotype distribution and the nature and frequency of l… Show more

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Cited by 58 publications
(70 citation statements)
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References 43 publications
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“…Canadian HBV/G was highly associated with MSM as a risk factor for infection, corresponding to previous studies (Bottecchia et al, 2008;Shibayama et al, 2005;Sánchez et al, 2007). When information is available regarding HBV/G co-infection, the co-infecting genotype is normally that which is highly prevalent within the geographical region, i.e.…”
supporting
confidence: 82%
See 1 more Smart Citation
“…Canadian HBV/G was highly associated with MSM as a risk factor for infection, corresponding to previous studies (Bottecchia et al, 2008;Shibayama et al, 2005;Sánchez et al, 2007). When information is available regarding HBV/G co-infection, the co-infecting genotype is normally that which is highly prevalent within the geographical region, i.e.…”
supporting
confidence: 82%
“…Despite the apparent low prevalence of HBV/G throughout the world, the viral genotype appears to circulate globally, as it has been reported in several European countries (De Maddalena et al, 2007;Jardi et al, 2008;Lacombe et al, 2006;Tran et al, 1991;Vieth et al, 2002), North and South America (Alvarado-Esquivel et al, 2006;Bottecchia et al, 2008;Kato et al, 2004;Osiowy & Giles., 2003;Sánchez et al, 2007), Nigeria (Olinger et al, 2006) and Asia (Shibayama et al, 2005;Suwannakarn et al, 2005;Toan et al, 2006). Canadian HBV/G was highly associated with MSM as a risk factor for infection, corresponding to previous studies (Bottecchia et al, 2008;Shibayama et al, 2005;Sánchez et al, 2007).…”
mentioning
confidence: 95%
“…Bottecchia et al (2008) identified genotype G in a patient infected with HBV only and in two patients co-infected with HIV. The current study is the second to identify the genotype among HIV co-infected patients.…”
Section: Discussionmentioning
confidence: 99%
“…HBV/G was described by Stuyver et al (2000) and, despite low prevalence, seems ubiquitous, as it has been reported in Europe (Lacombe et al, 2006;Vieth et al, 2002), the Americas (Alvarado-Esquivel et al, 2006;Alvarado Mora et al, 2011;Bottecchia et al, 2008;Chu et al, 2003;Osiowy et al, 2008), Asia (Shibayama et al, 2005;Toan et al, 2006) and Africa (Olinger et al, 2006;Toan et al, 2006). HBV/G is frequently reported in patients infected with human immunodeficiency virus (HIV) (Dao et al, 2011;Zehender et al, 2003), particularly in men who have sex with men (MSM) (Bottecchia et al, 2008;Osiowy et al, 2008). Patients co-infected with HBV/ G and HIV have an increased risk of liver fibrosis compared with those infected with other HBV genotypes Downloaded from www.microbiologyresearch.org by IP: 18.236.120.13…”
mentioning
confidence: 90%