Hepatitis B virus and human T-cell lymphotropic virus type 1 co-infection in the Northern Territory, Australia

Marr, Ian; Davies, Jane; Baird, Robert W.

doi:10.1016/j.ijid.2017.03.010

Cited by 10 publications

(15 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a previous study, 26 a co-infection rate of 0.5% was found for HBV/HCV, while a rate of 1.1% was reported for HBV/HTLV-1 co-infection, which is nearly the same as our study. On the other hand, in a survey conducted in Australia in 2017, 27 the sero-prevalence of HTLV-1 among HBVinfected patients was 14.4%, which is much higher than the 1.17% found in our study. These discrepancies may be the result of heterogeneity in patient populations studied in different geographical regions.…”

Section: Discussioncontrasting

confidence: 89%

Prevalence and Associated Risk Factors of HTLV-1 and Co-infections of Blood-Borne Viruses in Birjand, Iran’s Eastern Border

et al. 2020

View full text Add to dashboard Cite

Background: Blood-borne viruses (BBVs) are one of the most important public health concerns. South Khorasan has a long border with Afghanistan and concern has risen there about blood-borne oncogenic viral infections. The aim of the present study was to evaluate the prevalence and associated risk factors of human T-lymphotropic virus 1 (HTLV-1) and co-infections of BBVs in Birjand, Iran’s eastern border. Methods: In this cross-sectional study, 3441 subjects were tested for sero-prevalence of HTLV-1 by ELISA. The data on demographic features, HTLV-1-related risk factors and other characteristics of the population were analyzed by Pearson chi-square and logistic regression tests. Finally, the co-infection of BBVs was evaluated in the study. Results: The prevalence of HTLV-1 was 0.3% (95% CI: 0.12–0.48). Notably, the sero-prevalence of HIV, hepatitis B virus (HBV), hepatitis D virus (HDV), and hepatitis C virus (HCV) in our previous studies was reported at 0%, 0.2%, 1.2% and 1.6%, respectively. The results indicated that the occurrence of HTLV-1 infection was associated only with the history of hospitalization (odds ratio [OR]: 0.27, 95% CI: 0.07–0.97, with P = 0.04). The co-infection of HBV with HCV was the most common (2.35%), while a co-infection rate of 1.17% was found for both HBV/HTLV-1 and HBV/HDV. Conclusion: Although a higher prevalence of the viruses was expected, it was close to the overall Iranian population. With respect to close relationship with an HTLV-1 endemic area (Mashhad and Neyshabour), the prevalence is very low; however, more attention is needed. Our findings reinforce the importance of increasing knowledge about BBV-related health risk behaviors to prevent the emergence of new cases, especially in low-risk populations.

show abstract

Section: Discussioncontrasting

confidence: 89%

Prevalence and Associated Risk Factors of HTLV-1 and Co-infections of Blood-Borne Viruses in Birjand, Iran’s Eastern Border

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The reactivity for anti‐HTLV‐1/2 was confirmed by immunoblot assay at the National Reference Laboratory of the National Institute Health, Peru. A positive result on the immunoblot is defined as the reactivity to both recombinant envelope proteins (Rgp21 and Rgp46‐I) and/or envelope gp46 according to the World Health Organisation (Marr et al ., ). All donor samples included in this study tested negative for anti‐HIV‐1/2 during the study period.…”

Section: (A) Prevalence Of Hbsag Anti‐hbc and Anti‐htlv‐1/2 Among Blmentioning

confidence: 97%

Prevalence of hepatitis B and human T‐lymphotropic virus infection among blood donors at a hospital in the south‐central highlands of Peru

Ramírez-Soto

Huichi-Atamari²

2017

Transfusion Medicine

View full text Add to dashboard Cite

“…In contrast, a study in the USA described an increase in the HCV viral load among HIV and/or HTLV-2 co-infected individuals ( Hisada et al 2003 ). Regarding HBV infection, HIV-1 and HTLV-1 single-infected individuals were found to have a higher rate of HBV antigenemia, suggesting reduced HBV clearance, and HIV/HTLV-1 co-infected patients showed no protective effects of these retroviruses against hepatitis B ( Moreira et al 2013 , Marr et al 2017 ). Taking together, HTLV-1 seems to positively affect HCV clearance and negatively affect HBV removal, whereas HTLV-2 has a negative effect on HBV clearance.…”

mentioning

confidence: 99%

Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C

Caterino–de–Araujo

Alves

Campos

et al. 2018

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

With this study, the authors hope to alert clinicians regarding the presence of human T-cell lymphotropic virus type 1 and 2 (HTLV-1/-2) infections in patients with viral hepatitis B and C in Brazil. HTLV-1/-2 were detected in 1.3% of hepatitis B virus (HBV)- and 5.3% of hepatitis C virus (HCV)-infected blood samples sent for laboratory viral load measurements. A partial association of human immunodeficiency virus (HIV)-1 and HTLV-1/-2 infection was detected in patients with HCV (HIV+, 27.3%), whereas this association was almost 100% in HBV-infected patients (HIV+, all except one). The high prevalence of HTLV-1/-2 infection among patients with hepatitis C was of concern, as HTLV-1/-2 could change the natural course of subsequent liver disease. The authors suggest including HTLV-1/-2 serology in the battery of tests used when following patients with viral hepatitis in Brazil, regardless of the HIV status.

show abstract

Hepatitis B virus and human T-cell lymphotropic virus type 1 co-infection in the Northern Territory, Australia

Cited by 10 publications

References 24 publications

Prevalence and Associated Risk Factors of HTLV-1 and Co-infections of Blood-Borne Viruses in Birjand, Iran’s Eastern Border

Prevalence and Associated Risk Factors of HTLV-1 and Co-infections of Blood-Borne Viruses in Birjand, Iran’s Eastern Border

Prevalence of hepatitis B and human T‐lymphotropic virus infection among blood donors at a hospital in the south‐central highlands of Peru

Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C

Contact Info

Product

Resources

About