2016
DOI: 10.1007/s10096-016-2689-6
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Abstract: Schistosomiasis is related to the development of liver fibrosis and portal hypertension. Chronic co-infection with HBV and Schistosoma has been associated in endemic areas with a higher risk for a more severe liver disease. However, no studies have assessed the real importance of this co-infection in non-endemic regions. This is a retrospective observational study of Sub-Saharan immigrants attending between October 2004 and February 2014. Patients with chronic HBV infection with and without evidence of schisto… Show more

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Cited by 7 publications
(6 citation statements)
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“…Estimates claim that over 200,000 people die every year from the immunosuppressive and carcinogenic effects of the infection [57]. It decreases resistance to other harmful diseases including hepatitis B, HIV and malaria [810]. It also increases rates of seizures, infertility and anaemia [11, 12].…”
Section: Introductionmentioning
confidence: 99%
“…Estimates claim that over 200,000 people die every year from the immunosuppressive and carcinogenic effects of the infection [57]. It decreases resistance to other harmful diseases including hepatitis B, HIV and malaria [810]. It also increases rates of seizures, infertility and anaemia [11, 12].…”
Section: Introductionmentioning
confidence: 99%
“…Two studies with more than 500 and more than 200 participants, respectively, investigated co-infection of schistosomiasis (with an emphasis on S. mansoni infection) and chronic hepatitis B because previous studies from endemic countriesmainly Egypt and Brazil-had indicated that co-infection was associated with the risk of aggravated liver disease. 15,[29][30][31] However, this could not be confirmed in the recent studies. 15,29 Strongyloidiasis.…”
Section: Resultsmentioning
confidence: 71%
“…15,[29][30][31] However, this could not be confirmed in the recent studies. 15,29 Strongyloidiasis. The prevalence for strongyloidiasis in the reviewed articles ranged from 10.7% to 38.1% when several diagnostic methods were combined (Table 2 16,18,23,[32][33][34][35] ).…”
Section: Resultsmentioning
confidence: 71%
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“… 28 , 29 Controversies regarding schistosoma‐associated liver fibrosis state that coinfection of schistosomiasis with chronic HBV is associated with more severe hepatic fibrosis. 30 , 31 , 32 , 33 Our results indicated that coinfection of schistosomiasis with chronic HBV might result in worse outcomes. CAVIN2 + MP(2) cannot be specifically divided into M1 or M2 due to the low expression of marker genes of M1( TNF , IL1B , IL12B ) and M2( ARG1 , IL10 ).…”
Section: Discussionmentioning
confidence: 71%