Hepatic Flow Parameters Measured with MR Imaging and Doppler US: Correlations with Degree of Cirrhosis and Portal Hypertension

Abstract

Hepatic flow parameters measured with MR imaging correlate with the severity of cirrhosis and portal hypertension. Doppler US parameters are only weakly correlated with portal pressure.

Can preoperative diffusion-weighted MRI predict postoperative hepatic insufficiency after curative resection of HBV-related hepatocellular carcinoma? A pilot study

“…Accordingly, although DW-MRI is potentially useful when other noninvasive tools have failed to assess liver fibrosis in patients with hepatitis C virus infection (which makes mostly micronodular structures in the liver) [14], it seems that DW-MRI with our current setting of 3-T MRI system is not applicable to patients with CHB. However, because the intra-and interobserver reliability of DW-MRI were proved to be significantly high in this study and various techniques are under investigation to improve the image quality [36][37][38][39][40], the usefulness of DW-MRI can be investigated again in the future for patients with CHB, especially for obese patients in whom LSM is often inadequate.…”

Timing bolus dynamic contrast‐enhanced (DCE) MRI assessment of hepatic perfusion: Initial experience

“…However, a small dose of contrast for DCE MR imaging also has several benefits, including: 1) providing a relatively linear relationship between signal intensity and concen- tration of contrast material (13)(14)(15); and 2) allowing for subsequent diagnostic MRI with a full bolus of contrast material. Fourth, our images were acquired once every four seconds while those of Annet et al (7) were acquired approximately once per second. Our lower temporal resolution may have resulted in reduced accuracy in the estimates of the arterial and portal venous input functions that are used to calculate the hepatic perfusion parameters.…”

“…For example, Annet et al (7) showed that hepatic flow parameters measured with MRI correlate with the severity of cirrhosis and portal hypertension. Another recent study reported the feasibility of using MR liver perfusion parameters as biomarkers for liver fibrosis (10).…”

Gd-EOB-DTPA-enhanced MRI for the assessment of liver function and volume in liver cirrhosis

“…In healthy livers, the longer MTT could be the result of uptake into hepatocytes, intracellular transport and subsequent biliary excretion, a process that is undoubtedly more time-consuming. The increasing irBF, as seen in Figure 2, could be interpreted as the result of the arterialisation that cirrhotic liver parenchyma has been shown to undergo with increasing disease severity [42].…”