Hepatic Arterial Infusion (HAI) chemotherapy proves to be advantageous in the treatment of experimental liver tumors

Superiority of combined chemo-embolization and portal infusion with 5-fluorouracil over locoregional infusion concepts in Novikoff hepatoma-bearing rats

“…Novikoff hepatoma cells are moderately chemo-sensitive to 5-FU ( Bartowski et al 1986;Berger et al 1986;Schlag et al 1988). In addition, 5-FU has the advantage of a distinct first pass effect, which leads to high concentrations in the infused liver and tumor areas (Aguiar et al 1987).…”

Superiority of combined chemo-embolization and portal infusion with 5-fluorouracil over locoregional infusion concepts in Novikoff hepatoma-bearing rats

“…Novikoff hepatoma cells are moderately chemo-sensitive to 5-FU ( Bartowski et al 1986;Berger et al 1986;Schlag et al 1988). In addition, 5-FU has the advantage of a distinct first pass effect, which leads to high concentrations in the infused liver and tumor areas (Aguiar et al 1987).…”

Superiority of combined chemo-embolization and portal infusion with 5-fluorouracil over locoregional infusion concepts in Novikoff hepatoma-bearing rats

“…Novikoff hepatoma cells are moderately chemo-sensitive to 5-FU ( Bartowski et al 1986;Berger et al 1986;Schlag et al 1988). In addition, 5-FU has the advantage of a distinct first pass effect, which leads to high concentrations in the infused liver and tumor areas (Aguiar et al 1987).…”

Superiority of combined chemo-embolization and portal infusion with 5-fluorouracil over locoregional infusion concepts in Novikoff hepatoma-bearing rats

“…Novikoff hepatoma cells are moderately chemo-sensitive to 5-FU ( Bartowski et al 1986;Berger et al 1986;Schlag et al 1988). In addition, 5-FU has the advantage of a distinct first pass effect, which leads to high concentrations in the infused liver and tumor areas (Aguiar et al 1987).…”