Hemorrhage of the Suprarenals in the New-Born Infant

Haemorrhagic necrosis of the adrenal gland in perinatal infants: A clinico‐pathological study

“…In a further two cases massive pulmonary haemorrhage was a complicating feature in the analysis of the symptomatology. Apart from the group of infants with septicaemia, pyrexia was not a feature of our series, which differs in this respect from the experience of Goldzieher and Greenwald (1928). Our findings are similar to those of Schaffer (1960) whose experience led him to state that there was no single diagnostic pattern.…”

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PLATES LXVIII-LXXIX SINCE they were first described by Spencer (1892), haemorrhagic lesions of the adrenal gland have been given many names and Symington (1969) lists five synonyms (of which haemorrhagic necrosis is one) that have been used at different times. In the perinatal period, adrenal haemorrhage, to use another of the synonyms, is thought to be a relatively uncommon lesion and many texts stress its association with either systemic infections (Kissane and Smith, 1967) or birth trauma (Stowens, 1966). Others have discussed the role of anoxia (Gruenwald, 1955;Morison, 1963).This paper presents our experience of this lesion in perinatal infants, and draws on personally studied cases and the records of the Department of Pathology of the Radcliffe Infirmary, Oxford.

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Syndrome of Suprarenal Haemorrhage in the Adult

“…A mass was palpated in the left loin; operation was performed, a clot evacuated, and a bleeding-point ligatured. Goldzieher and Greenwald (1928) report the case of a newborn infant presenting typical signs of unilateral suprarenal haemorrhage, with a palpable mass in the right flank. Immediate response occurred to injections of suprarenal cortical extract, characterizedchiefly by a fall in the resp%ratory rate from 60 to 30 a minute half an hour after the injection, together with improvement in the general condition.…”