Hémorragie sous-conjonctivale bilatérale massive révélatrice d’une leucémie aiguë lymphoblastique

Malek, Ines; Chebbi, A.; Bouladi, M; Nacef, Leila; Bouguila, H.; Ayed, SI

doi:10.1016/j.jfo.2012.03.013

Cited by 13 publications

(3 citation statements)

References 17 publications

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“…Pathologies of the coagulation system, including the disorders associated with thrombocytopenia and platelet dysfunction, such as thrombocytopenic purpura, anemia, leukemia, splenic disorders, anticoagulant or antiplatelet therapy, and uremia, may cause bleeding in conjunctival vessels 2,53,54–59…”

Section: Systemic Factorsmentioning

confidence: 99%

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Subconjunctival hemorrhage: risk factors and potential indicators

Tarlan¹,

Kıratlı²

2013

OPTH

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Subconjunctival hemorrhage is a benign disorder that is a common cause of acute ocular redness. The major risk factors include trauma and contact lens usage in younger patients, whereas among the elderly, systemic vascular diseases such as hypertension, diabetes, and arteriosclerosis are more common. In patients in whom subconjunctival hemorrhage is recurrent or persistent, further evaluation, including workup for systemic hypertension, bleeding disorders, systemic and ocular malignancies, and drug side effects, is warranted.

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Section: Systemic Factorsmentioning

confidence: 99%

“…An unusual bilateral massive spontaneous SCH can be an initial sign of acute lymphoblastic leukemia as a result of blood dyscrasia 54. Another example for one of the same underlying serious conditions is idiopathic thrombocytopenic purpura, which can present with isolated unilateral SCH 53.…”

Section: Systemic Factorsmentioning

confidence: 99%

Subconjunctival hemorrhage: risk factors and potential indicators

Tarlan¹,

Kıratlı²

2013

OPTH

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“…In addition, coagulation factor deficiency was detected in less than 1% of patients (10) . During anticoagulant and antiaggregant usage, and hemostatic alterations as immune thrombocytopenia, congenital bleeding disorders and hematologic malignancy as leukemia, SCH was reported in previous cases [3,[9][10][11] . However, in these cases SCH is considered to be a part of other mucocutaneous bleeding, and patients often apply to the hematology outpatient clinic.…”

Section: Discussionmentioning

confidence: 97%

Do We Need To Evaluate Patients With Spontaneous Subconjunctival Hemorrhage For Bleeding Disorders?

Sayın

Yener²

2021

Preprint

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Aim of the study: Subconjunctival hemorrage (SCH) is a frequent bleeding manifestation and a common cause of visits to the primary care. Trauma in young patients and vascular damage such as hypertension in the elderly are the most common causes of SCH and the prevalence of hematological diseases is less than 1%. We aimed to evaluate the prevalence of congenital or acquired bleeding disorders in patients with once or recurrent SCH. Methods used to conduct the study: It is a retrospective study and included fifty-two patients with SCH whose etiologic factor was not detected. Hemostatic tests were studied in 52 patients (25 male and 27 females) with. All patients included were evaluated for congenital or acquired bleeding disorder and SCH with once and those with 2 or more were compared for the laboratory results. Results of the study: One patient with once and one patient with recurrent SCH (3.8%) were diagnosed a type I von Willebrand disease (vWD). The prevalence of patients with type 1 vWD in the study was not statistically significant when compared with the frequency of von Willebrand favctor (vWF) deficiency in the normal population. Fibrinogen level was found to be statistically higher in patients who had SCH once than those who had recurrent SCH. But fibrinogen level was in normal range in all patients. Conclusions drawn from the study and clinical implications: There was no increase in the incidence of congenital or acquired bleeding disorder in SCH patients compared to normal population. Therefore, it was considered that spontaneous SCH patients do not need to be evaluated for bleeding disorder.

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Massive spontaneous subconjunctival hemorrhage in a patient on therapeutic warfarin: A case report

Philip

Fry

Hermanson

et al. 2021

American Journal of Ophthalmology Case Reports

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Purpose To describe a case of massive spontaneous subconjunctival hemorrhage in a patient taking warfarin with a therapeutic international normalized ratio (INR). Observations Massive circumferential hemorrhagic chemosis, extensive periorbital and facial ecchymosis, and active arterial extravasation in the subconjunctiva which required cessation and reversal of anticoagulation. Findings gradually resolved over several months after discharge. Conclusions and importance While subconjunctival hemorrhage, even in anticoagulated patients, is usually benign, rare examples of severe presentations exist. We present, to our knowledge, the first documented case of a subconjunctival hemorrhage necessitating cessation and reversal of anticoagulation in the setting of a therapeutic INR.

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Hémorragie sous-conjonctivale bilatérale massive révélatrice d’une leucémie aiguë lymphoblastique

Cited by 13 publications

References 17 publications

Subconjunctival hemorrhage: risk factors and potential indicators

Subconjunctival hemorrhage: risk factors and potential indicators

Do We Need To Evaluate Patients With Spontaneous Subconjunctival Hemorrhage For Bleeding Disorders?

Massive spontaneous subconjunctival hemorrhage in a patient on therapeutic warfarin: A case report

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