Hemorheology and oxidative stress in patients with differentiated thyroid cancer following I-131 ablation/metastasis treatment

Şengöz, Tarık; Kilic‐Toprak, Emine; Yaylalı, Olga; Kilic-Erkek, Ozgen; Özdemir, Yasin; Oymak, Burak; Şenol, Hande; Yüksel, Doğangün; Küçükatay, Vural; Bor-Küçükatay, Melek

doi:10.3233/ch-190717

Cited by 6 publications

(2 citation statements)

References 43 publications

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“…Regarding erythrocyte deformability, it was found to be significantly lower in patients with differentiated thyroid cancers than in healthy individuals and was not modified after radioiodine treatment. Interestingly, the modification of oxidant–antioxidant stress values was not observable post-treatment, as well [ 42 ]. Comparing normal controls and multiple myeloma patients, a significant decrease in erythrocyte deformability was observed in cancer patients [ 43 ].…”

Section: Erythrocyte Nak-atpase and Deformability In Various Patho/physiological Situationsmentioning

confidence: 99%

Erythrocyte Deformability and Na,K-ATPase Activity in Various Pathophysiological Situations and Their Protection by Selected Nutritional Antioxidants in Humans

Radošinská

Vrbjar

2021

IJMS

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The physicochemical and functional properties of erythrocytes are worsened in a variety of diseases. Erythrocyte deformability refers to their ability to adjust their shape according to external forces exerted against them in the circulation. It is influenced by the functionality of the Na,K-ATPase enzyme, which is localized in their membranes. The proposed review is focused on knowledge regarding changes in erythrocyte Na,K-ATPase activity, and their impact on erythrocyte deformability in various pathophysiological situations observed exclusively in human studies, as well as on the potential erytroprotective effects of selected natural nutritional antioxidants. A clear link between the erythrocyte properties and the parameters of oxidative stress was observed. The undesirable consequences of oxidative stress on erythrocyte quality and hemorheology could be at least partially prevented by intake of diverse antioxidants occurring naturally in foodstuffs. Despite intensive research concerning the effect of antioxidants, only a small number of investigations on erythrocyte properties in humans is available in databases. It is worth shifting attention from animal and in vitro experiments and focusing more on antioxidant administration in human studies in order to establish what type of antioxidant, in what concentration, and in which individuals it may provide a beneficial effect on the human organism, by protecting erythrocyte properties.

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Section: Erythrocyte Nak-atpase and Deformability In Various Patho/physiological Situationsmentioning

confidence: 99%

Erythrocyte Deformability and Na,K-ATPase Activity in Various Pathophysiological Situations and Their Protection by Selected Nutritional Antioxidants in Humans

Radošinská

Vrbjar

2021

IJMS

View full text Add to dashboard Cite

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“…Tüm bu sayılanlara rağmen hiçbir hakem ya da okuyucu hemoreolojik parametre yazılmış ama sadece şunlar çalışılmış ya da sadece şu parametrelere ait literatür tartışılmış gibi eleştiri/geri bildirimlerle dönüş yapmamıştır. Çünkü bahsedilen konu ile ilgili yeterli bilgiye sahip hakem ve okuyucular makalenin planlanması, "In microcirculation, rheological characteristics of blood (i.e., erythrocyte deformability and aggregation, plasma viscosity) are the major determinants of resistance to flow and their alterations are known to impair microcirculatory blood flow[3][4][5]." denmektedir.…”

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