Hemodynamic study of 85 patients with borderline hypertension

Safar, Michel E.; Weiss, Y; Levenson, Jaime; London, Gérard M.; Milliez, P

doi:10.1016/0002-9149(73)90261-0

Cited by 126 publications

(24 citation statements)

References 15 publications

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“…Validation for these calculations had been previously performed in our laboratory, using intra-arterial measurements. 8 Heart rate (beats per minute) was determined on the basis of the ECG recording immediately after the blood pressure determination.…”

Section: Measurement Of Arterial Pressure and Heart Ratementioning

confidence: 99%

Increased pulse pressure in patients with arteriosclerosis obliterans of the lower limbs.

Me¹,

Totomoukouo²,

Asmar³

et al. 1987

Arteriosclerosis

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Section: Measurement Of Arterial Pressure and Heart Ratementioning

confidence: 99%

Increased pulse pressure in patients with arteriosclerosis obliterans of the lower limbs.

Me¹,

Totomoukouo²,

Asmar³

et al. 1987

Arteriosclerosis

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“…CO was measured at least twice with the subject in the supine position and during 3 and 5 minutes of 50-degree, weight-bearing, head-up tilt. 5 Particular care was taken to ensure accurate blood pressure determinations by having the subject's arm extended, so that the pressure transducers, needles, and tubing were at the atrial level at all times. In addition, the pressure transducers were calibrated and referred to zero pressure during all supine, tilt, and posttilt testing.…”

Section: Hemodynamic Measurements and Tilt Test Techniquementioning

confidence: 99%

Tilt test in essential hypertension. Differential responses in heart rate and vascular resistance.

London¹,

Weiss²,

Pannier³

et al. 1987

Hypertension

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SUMMARY Changes in hemodynamic parameters following 50-degree head-up tilt were studied in a population of 56 men, including 35 subjects with sustained essential hypertension and 21 agematched normotensive controls. The increase in heart rate following tilt was similar in both groups and exhibited the same reduction in response with age. The increase in vascular resistance following tilt was strongly and positively correlated with both age and baseline vascular resistance. The latter finding was observed mainly in hypertensive subjects. The study provided evidence that differentiated responses of heart rate and vascular resistance may be observed following orthostasis. In both normal and hypertensive subjects, the age dependence of heart rate response possibly reflected differences in baroreceptor reflex control of parasympathetic and sympathetic activity. In hypertensive subjects, the vascular response was amplified with age and baseline vascular resistance, suggesting a role for structural changes of the vessels in the increased vascular response. (Hypertension 10: 29-34, 1987) KEY WORDS • essential hypertension • baroreceptor reflex mechanisms • orthostasis W HEN a normal person changes from the recumbent to the erect position, the central blood volume and heart volume are decreased and the cardiac output (CO) is reduced by about 20%.'" 3 Diminished CO accompanying reduced peripheral resistance should result in a sharp fall in arterial pressure unless reflex cardioacceleration and vasoconstriction occur at the same time because of the baroreceptor reflex compensatory mechanisms.3 For that reason, baroreceptor reflex mechanisms may be adequately evaluated using passive tilting on a tilt table from the horizontal to the erect position, 4 " 8 during which muscular pumping action of the legs 9 is minimal or absent.The mechanisms resulting in the changes in heart rate and systemic vascular resistance on standing are complex, involving baroreceptors of the high and the low pressure systems and even ergoreceptors in the skeletal muscles.3 ' ltM5 Furthermore, adequate studies

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“…8 In recent years, several studies have shown that accelerated heart rate is an independent precursor of hypertension. 9,10 However, some studies have shown that after adjustment for blood pressure, the role of heart rate was not significant in the development of future hypertension.…”

Section: Introductionmentioning

confidence: 99%

Association between 24-hour ambulatory heart rate and arterial stiffness

Albaladéjo

Asmar

et al. 2000

J Hum Hypertens

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Clinical and experimental studies point to a positive association between carotid-femoral pulse wave velocity (PWVcf) and casual heart rate. However, an association with 24-h ambulatory heart rate has never been investigated. Twenty-four hour ambulatory heart rate and PWVcf (automatic computerised technique) were simultaneously measured in 213 subjects with untreated mild-to-moderate essential hypertension. It was found that mean ambulatory heart rate was higher in women than in men but the difference reached statistical significance only in those below 50 years of age during night-time measurements. As well as age and blood

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Hemodynamic study of 85 patients with borderline hypertension

Cited by 126 publications

References 15 publications

Increased pulse pressure in patients with arteriosclerosis obliterans of the lower limbs.

Increased pulse pressure in patients with arteriosclerosis obliterans of the lower limbs.

Tilt test in essential hypertension. Differential responses in heart rate and vascular resistance.

Association between 24-hour ambulatory heart rate and arterial stiffness

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