volume 66, issue 9, P5561-5568 1992
DOI: 10.1128/jvi.66.9.5561-5568.1992
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Abstract: Feline leukemia viruses (FeLVs) belonging to interference subgroup C induce fatal anemia resembling human pure red cell aplasia (PRCA). Subgroup A FeLVs, although closely related genetically to FeLVs of subgroup C, do not induce PRCA. The determinants for PRCA induction by a molecularly cloned prototype subgroup C virus (FeLV-Sarma-C [FSCJ) have been localized to the N-terminal 241 amino acids of the surface glycoprotein (SU) gp7O. To investigate whether the anemogenic activity of FSC reflects a unique capacit…

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