Healthcare workers’ knowledge, attitudes and behaviours with respect to antibiotics, antibiotic use and antibiotic resistance across 30 EU/EEA countries in 2019

Ashiru‐Oredope, Diane; Hopkins, Susan; Vasandani, Sagar; Umoh, Eno; Oloyede, Olaolu; Nilsson, Andreas; Kinsman, John; Elsert, Linda; Monnet, Dominique

doi:10.2807/1560-7917.es.2021.26.12.1900633

Cited by 56 publications

(75 citation statements)

References 22 publications

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“…Nevertheless, appropriate understanding and knowledge of prudent antimicrobial use, and the spread of antimicrobial-resistant microorganisms are important drivers for the prevention and control of AMR [ 18 , 19 , 20 ]. Behavior change in favor of improving antibiotic use and resistance outcomes is an essential strategy; a framework to address this behavior change was devised by the European Centre for Disease Prevention and Control and was adopted by the present study [ 13 , 21 ]. This framework addressed capabilities, opportunities, and motivations that facilitate correct behavior (COM-B).…”

Section: Introductionmentioning

confidence: 99%

Pharmacists’ Knowledge, Attitudes, Behaviors and Information Sources on Antibiotic Use and Resistance in Jordan

et al. 2022

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Antimicrobial resistance (AMR) is a serious healthcare problem that affects public health globally. Appropriate understanding and knowledge of prudent antimicrobial use and resistance, along with providing evidence-based information sources, are needed for informed antibiotic prescribing practices. This study aimed to assess the knowledge, opportunity, motivation, behavior of pharmacists and their information sources regarding antibiotic use and resistance in Jordan. An online cross-sectional questionnaire was developed and administered to pharmacists during the period of July–September 2021. The survey is an adapted version of the validated European Centre for Disease Prevention and Control (ECDC) survey for antibiotic use and resistance. Pharmacists from all sectors (n = 384), of whom 276 (71.9%) were community pharmacists, completed an online questionnaire. While respondents scored highly (>87%) on knowledge on effective use, unnecessary use, and associated side effects of antibiotics, lower scores were recorded for knowledge on the spread of antibiotic resistance (52.9%). Pharmacists support easy access to guidelines on managing infections in 56% of cases, and easy access to materials advising prudent antibiotic use and resistance in 39.8% of cases. One-third of respondents (37.0%) reported no knowledge of any initiatives on antibiotic awareness and resistance. Pharmacists were aware (13.3%), unaware (36.2%), or unsure (50.5%) of the existence of a national antibiotic resistance action plan. Pharmacists indicated an interest in receiving more information on resistance to antibiotics (55.2%), medical conditions for which antibiotics are used (53.1%), how to use antibiotics (45.1%), prescribing of antibiotics (34.4%), and links between the health of humans, animals, and the environment (28.6%). Findings can inform antimicrobial stewardship with required interventions to improve antibiotic use.

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Section: Introductionmentioning

confidence: 99%

Pharmacists’ Knowledge, Attitudes, Behaviors and Information Sources on Antibiotic Use and Resistance in Jordan

et al. 2022

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“…To our knowledge, this is the first study in the Middle East area to assess the knowledge, attitudes and behaviors about antibiotic use and antibiotic resistance among physicians and dentists using the ECDC's validated instrument [22,23]. Antimicrobial resistance is an emerging health threat worldwide, driving a real necessity for rational antibiotic use and following guidelines in treating patients to preserve antimicrobial activity [24,25].…”

Section: Discussionmentioning

confidence: 99%

“…A cross-sectional study survey of Jordanian physicians and dentists was conducted using an online questionnaire. This survey was conducted using the European Centre for Disease Prevention and Control's (ECDC) validated instrument [22,23].…”

Section: Study Design and Settingmentioning

confidence: 99%

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Prescribers’ Knowledge, Attitudes and Behaviors on Antibiotics, Antibiotic Use and Antibiotic Resistance in Jordan

et al. 2021

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More research is needed on the drivers of irrational antibiotic prescribing among healthcare professionals and to ensure effective prescribing and an adequate understanding of the issue of antibiotic resistance. This study aimed at evaluating prescribers’ knowledge, attitudes and behaviors about antibiotic use and antibiotic resistance. A cross-sectional study was conducted utilizing an online questionnaire and included physicians and dentists from all sectors in Jordan. A total of 613 prescribers were included (physicians n = 409, dentists n = 204). Respondents’ knowledge on effective use, unnecessary use or associated side effects of antibiotics was high (>90%), compared with their knowledge on the spread of antibiotic resistance (62.2%). For ease of access to the required guidelines on managing infections, and to materials that advise on prudent antibiotic use and antibiotic resistance, prescribers agreed in 62% and 46.1% of cases, respectively. 28.4% of respondents had prescribed antibiotics when they would have preferred not to do so more than once a day or more than once a week. Among respondents who prescribed antibiotics, 63.4% would never or rarely give out resources on prudent use of antibiotics for infections. The findings are of importance to inform antibiotic stewardships about relevant interventions aimed at changing prescribers’ behaviors and improving antibiotic prescribing practices.

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“…Researchers worldwide are combining their efforts to discover and develop new vital antimicrobials to minimize this growing problem [1][2][3] . Owing to the overuse of broad-spectrum antibiotics to treat infections in humans, their excessive use in agriculture, and poor infection control in hospitals, resistant pathogens have become a serious threat to public health [4][5][6] . As such, a database was procured to predict the existence of nearly more than 20,000 undiscovered resistance genes (r genes) of almost 400 different types of the r genes predicted in the main from available bacterial genome sequences 7,8 .…”

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confidence: 99%

Screening and Characterization of Soil Microbes Producing Antimicrobial Compounds in Makkah Province, Saudi Arabia

Alharbi

Al-harthi

Alsamadani

et al. 2021

Biosci., Biotech. Res. Asia

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This study aimed to investigate a method to manage antimicrobial resistance (AMR) issues by exploring soil microorganisms that are capable of producing bioactive compounds. Eight different types of soil were selected from three locations to screen, isolate, and identify microorganisms that are capable of producing antimicrobial compounds. The multi-drug resistant strains are Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans were selected for primary and secondary screening using the crowded plate method and the agar well diffusion method. Inhibition zones were measured, and data were assessed using statistical tests to check for normality and differences between parametric variables and nonparametric data. This was followed by biochemical characterization, DNA isolation, and polymerase chain reaction (PCR). Molecular identification was performed using 16S rRNA amplification and sequencing. Here, 86 isolates containing bacteria and fungi were successfully extracted from soil samples. Further, 49 of 86 microbes showed possible antimicrobial activity, but only 12 isolates resulted in distinct inhibition zones with the selected multi-drug resistant strains. The following different taxa were identified: Firmicutes (nine strains), Proteobacteria (one strain), Actinobacteria (one strain), and Azotobacter (one strain). Species are represented in a phylogenetic tree, which was constructed using the unweighted pair-group method with arithmetic mean (UPGMA) method. The evolutionary distances were computed using the Maximum Composite Likelihood method. The identified microorganisms showed antimicrobial activity, confirming that soil microorganisms have great potential to address AMR issues.

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Healthcare workers’ knowledge, attitudes and behaviours with respect to antibiotics, antibiotic use and antibiotic resistance across 30 EU/EEA countries in 2019

Cited by 56 publications

References 22 publications

Pharmacists’ Knowledge, Attitudes, Behaviors and Information Sources on Antibiotic Use and Resistance in Jordan

Pharmacists’ Knowledge, Attitudes, Behaviors and Information Sources on Antibiotic Use and Resistance in Jordan

Prescribers’ Knowledge, Attitudes and Behaviors on Antibiotics, Antibiotic Use and Antibiotic Resistance in Jordan

Screening and Characterization of Soil Microbes Producing Antimicrobial Compounds in Makkah Province, Saudi Arabia

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