2020
DOI: 10.1590/1516-4446-2019-0739 View full text |Buy / Rent full text
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Abstract: Objective: To assess health-related quality of life and associated factors in patients treated with atypical antipsychotics, as well as to determine utility values using the EuroQol-5D-3L instrument. Methods: A cross-sectional study was conducted at a state-run pharmacy in the Brazilian National Health System. Individuals were included if they were using a single atypical antipsychotic and completed the EuroQol-5D-3L. Sociodemographic, behavioral, and clinical data were… Show more

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“…In South America, one study from Brazil (de Almeida et al, 2020 ), whose information was considered low-quality, found no significant differences in the rates of Afro-Brazilian or mixed heritage service-users in receiving clozapine treatment compared to Caucasian and Asian people ( Table 1 ).…”
Section: Resultsmentioning
“…This disparity was present in studies that controlled for various demographic and clinical covariates including treatment-resistance. In the only study included in the review from Brazil, no significant differences were reported in the rates of receiving clozapine for service-users of mixed race or Afro-Brazilian descent compared to those of Asian or Caucasian backgrounds (de Almeida et al, 2020 ). Mixed findings were observed regarding clozapine treatment within Asian communities in the UK (Cho et al, 2019 ; Das-Munshi et al, 2018 ; Govind et al, 2020 ; Kesserwani et al, 2019 ).…”
Section: Discussionmentioning
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“…The VAS scale was used in this paper in order to evaluate the self-reported health status of the individuals rather than the utility score provided by the EQ-5D. This decision was supported by a paper recently published by Almeida et al [27], which evaluated the influence of atypical antipsychotic usage on QOL and revealed that the VAS scale could be useful to address further factors influencing the self-perceived health status of the patients.…”
Section: Variablesmentioning
“…A broad understanding of antipsychotics and their effects on movement disorders associated with dose and treatment length is relevant. Since these adverse effects directly impact the quality of life of individuals undergoing these medications, such as problems with mobility, self-care, daily activities, anxiety, and depression 15 . Knowing that there are still disagreements in the literature about the dosage and duration of treatment associated with the use of antipsychotics and their adverse effects on movement, the objective of the present study was to identify movement disorders induced by the use of antipsychotics.…”
Section: Introductionmentioning