Health-related quality of life in men with erectile dysfunction

Litwin, Mark S.; Nied, Robert J.; Dhanani, Nasreen

doi:10.1046/j.1525-1497.1998.00050.x

Cited by 268 publications

(233 citation statements)

References 33 publications

(33 reference statements)

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“…34 Recognition of sexual dysfunction may be a powerful motivator for lifestyle change in middle-aged and older men. Moreover, both ED 35 and LUTS 36 are associated with increased cardiovascular risk, adversely affect quality of life and mood and interfere with interpersonal relationships, often necessitating medication or surgery. In contrast, we have shown that a simple lifestyle intervention is effective in improving sexual and urinary dysfunction in obese men.…”

Section: Discussionmentioning

confidence: 99%

“…The International Prostate Symptom Scale (IPSS) is a series of questions used to assess the severity of irritative (frequency, urgency, nocturia) and obstructive LUTSs (incomplete emptying, intermittency, weak stream, straining), attributable to bladder outlet obstruction caused by prostatic enlargement. 19 Symptoms are classified as mild (score 0-7), moderate (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19) or severe (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35).…”

Section: Questionnairesmentioning

confidence: 99%

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Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men

et al. 2010

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Objective: Abdominal obesity and type 2 diabetes mellitus are associated with erectile and urinary dysfunction in men. The extent to which sexual function and lower urinary tract symptoms (LUTSs) are improved by weight loss remains unclear. Subjects: We compared the effects of 8 weeks of a low-calorie diet using meal replacements (Kicstart) on insulin sensitivity, plasma testosterone levels, erectile function (measured by the five-item version of the International Index of Erectile Function, IIEF-5), sexual desire (measured by the Sexual Desire Inventory, SDI) and LUTS (measured by the International Prostate Symptom Score, IPSS), in abdominally obese (body mass index X30 kg m À2 , waist circumference (WC) X102 cm) men (mean age 49.7 years) with uncomplicated diet or oral hypoglycemic-treated type 2 diabetes mellitus (n ¼ 19) or without type 2 diabetes mellitus (n ¼ 25), with a control group of nondiabetic men (n ¼ 26) with similar body mass index and WC. Results: Weight loss of B10% was significantly associated with increased insulin sensitivity, plasma testosterone levels, IIEF-5 and SDI scores, as well as reduced WC and IPSS scores, in diabetic as well as nondiabetic men. The degree of weight loss was significantly associated with improvements in plasma testosterone levels (r ¼ À0.34), erectile function (r ¼ À0.26) and LUTS (r ¼ 0.65). Reduction in LUTS was significantly associated with increased plasma testosterone (r ¼ À0.35), erectile function (r ¼ À0.42) and sexual desire (r ¼ À0.40). Conclusions: Diet-induced weight loss significantly and rapidly improves sexual function, and reduces LUTS, in obese middleaged men with or without diabetes.

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Section: Discussionmentioning

confidence: 99%

Section: Questionnairesmentioning

confidence: 99%

Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men

et al. 2010

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“…29 The SF-36 has been used extensively in research on men with prostate carcinoma and quality of life as well as in research on men seeking help for ED, 30 allowing us to compare our survey sample with similar cohorts of men. We predicted that men with better perceived physical and mental health also would have better sexual outcomes.…”

Section: Methodsmentioning

confidence: 99%

“…35 Our sample's scores also were similar to norms established in other large registries for patients with prostate carcinoma on the SF-36 and the UCLA PCI urinary and bowel function scales. 28,30 …”

Section: Sexual Outcomesmentioning

confidence: 99%

Defining sexual outcomes after treatment for localized prostate carcinoma

Schover

Fouladi

Warneke

et al. 2002

Cancer

287

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BACKGROUNDThe objective of this survey was to identify factors associated with good sexual outcomes in a large group of survivors of localized prostate carcinoma.METHODSA postal survey was sent to 2636 men in the Cleveland Clinic Foundation's Prostate Cancer Registry who either were treated with definitive radiotherapy or underwent prostatectomy for localized prostate carcinoma. The survey asked about demographic items, past and current sexual functioning, partner's sexual function and health, and a number of factors hypothesized to affect sexual satisfaction. Standardized questionnaires included the Sexual Self‐Schema Scale‐Male Version, the International Index of Erectile Function (IIEF), urinary and bowel symptom scales from the Los Angeles Prostate Cancer Index, and the Short Form Health Survey (SF‐36).RESULTSThe return rate was 49%, yielding a sample of 1236 men at an average of 4.3 years post‐treatment. Comparing responders with nonresponders suggested that the sample may have been somewhat biased toward men who were more interested in maintaining sexual function. At the time they were diagnosed with prostate carcinoma, 36% of men had erectile dysfunction (ED). Within the past 6 months, however, 85% of men reported having ED. Only 13% of men were having reliable, firm erections spontaneously, and another 8% of men were having erections with the aid of a medical treatment. Men were as distressed about loss of desire and trouble having satisfying orgasms as they were about ED. Of the 84% of men who reported having a current sexual partner, 66% indicated that she had a sexual problem. Younger age was associated strongly with better sexual outcome (global IIEF score). With demographic factors taken into account, better sexual outcome was related significantly to medical factors, including not having neoadjuvant or current antiandrogen therapy, undergoing bilateral nerve‐sparing prostatectomy or brachytherapy, and having better mental and physical health composite scores on the SF‐36. Sexual factors that were associated with a better outcome included having normal erections before treatment for prostate carcinoma, choosing a treatment based on the hope that it would preserve sexual function, having more sexual partners in the past year, and having a sexually functional partner.CONCLUSIONSThe great majority of men who survive prostate carcinoma do not achieve a return to functional sexual activity in the years after treatment. The priorities a man places on sexuality and on having a sexually functional partner are important factors in sexual satisfaction at follow‐up, over and above the influence of age and medical factors. Cancer 2002;95:1773–85. © 2002 American Cancer Society.DOI 10.1002/cncr.10848

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“…En un estudio realizado en un grupo de pacientes en hemodiá lisis, el dominio emocional del cuestionario SF-36 está muy asociado con la DE independientemente de otras comorbilidades 15 . Cabe destacar que aunque en algú n caso se ha descrito una asociació n predominante de la DE con los dominios físicos de la calidad de vida, reflejada por el cuestionario MOS-SF36 16 , se afectan preferentemente los dominios emocionales 17 .…”

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