Health-Related Quality of Life Among Patients with Postmenopausal Osteoporosis Treated with Weekly and Monthly Bisphosphonates

Kaštelan, Darko; Vlak, Tonko; Lozo, Petar; Gradišer, Marina; Mijic, Sime; Nikolić, Tatjana; Miškić, Blaženka; Car, Dolores; Tajsić, Gordana; Dušek, Tina; Jajić, Zrinka; Grubišić, Frane; Poljičanin, Tamara; Bakula, Miro; Dzubur, Fedja; Strizak-Ujevic, Matilda; Kadojić, Mira; Radman, Miroslav; Vugrinec, Maja; Kuster, Zeljka; Pekez, Marijeta; Radović, Endi; Labar, Ljubica; Crnčević-Orlić, Željka; Koršić, Mirko

doi:10.3109/07435800.2010.505218

Cited by 12 publications

(10 citation statements)

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“…In a prospective, multicenter study, the QoL was assessed in patients with postmenopausal OP who were treated with weekly and monthly oral bisphosphonates. [ 25 ] The study included patients who were treated with weekly ALN or risedronate for at least six months prior to enrolment. All patients were switched from weekly bisphosphonates to monthly IBNs without a wash-out period.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of pain, quality of life, and patient satisfaction in parenterally treated patients with postmenopausal osteoporosis

Özsoy-Ünübol¹,

Akyüz

Mirzayeva

et al. 2020

Turk J Phys Med Rehab

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Section: Discussionmentioning

confidence: 99%

Evaluation of pain, quality of life, and patient satisfaction in parenterally treated patients with postmenopausal osteoporosis

Özsoy-Ünübol¹,

Akyüz

Mirzayeva

et al. 2020

Turk J Phys Med Rehab

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“…Another strength of our study was the evaluation of HRQoL by means of the mini-OQLQ. Effects of ibandronate on HRQoL have seldom been assessed [15,16]. Our results suggest that all aspects of QoL may improve with ibandronate, which should be a primary goal of antiresorptive therapy according to some authors [17].…”

Section: Discussionmentioning

confidence: 87%

Clinical Effects of a 6-Month Treatment Course of Ibandronate, Vitamin D, and Calcium in Postmenopausal Women from Central America: Results of a Multinational, Prospective Pilot Study

Gutierrez¹,

Codina

Pinel

et al. 2016

Integr Med Int

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Background/Aims: To explore the effects of ibandronate plus a supplementation of vitamin D and calcium on bone mineral density (BMD) and health-related quality of life (HRQoL) in a sample of postmenopausal women from Central America. Secondarily, factors related to the magnitude of improvements in BMD after treatment were investigated. Methods: Postmenopausal women with idiopathic osteoporosis or at risk of developing it, who were going to start treatment with ibandronate 150 mg once a month plus daily supplementation with vitamin D 400-800 IU and calcium 500-1,000 mg, were followed up for 6 months. BMD, HRQoL (mini-Osteoporosis Quality of Life Questionnaire), and treatment adherence (Morisky scale) were studied before and after treatment. Results: Four hundred and twenty-five women were assessed at baseline, and 308 (72%) were reassessed at month 6. Lumbar spine, proximal femur, and hip BMD increased by 3.35 ± 0.75, 1.88 ± 0.50, and 2.75 ± 0.32%, respectively (p < 0.001 for all). HRQoL total score and emotional functioning, symptoms, physical function, and leisure subscores improved by 26-49% (p < 0.01 in all cases). Lower body mass index, younger age at menopause, use of corticoids, and higher adherence were significantly and independently associated with a greater improvement in lumbar spine BMD (logistic regression). Conclusion: Improvements in BMD and HRQoL after ibandronate, vitamin D, and calcium were observed in patients from Central America, which should be confirmed by double-blind, randomized, controlled trials. Lack of adherence to ibandronate was related to worse outcomes, thus highlighting the need for work on this issue with patients on treatment.

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“…The existence of the Department of Physical and Rehabilitation Medicine in Split, Croatia has enabled advancement opportunities for young professionals, including both professional and scientific development, which will be reflected in increased number of publications [18][19][20][21][22][23]. Education of scientific and teaching staff was undertaken to enable further prosperity of rehabilitation medicine at the University of Split.…”

Section: Development Of Prm Training Center In Split Croatiamentioning

confidence: 99%

Physical and rehabilitation medicine training center in Split, Croatia: striving to achieve excellence in education of a rehabilitation team

Vlak

Šošo

Poljičanin

et al. 2013

Disability and Rehabilitation

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Academic setting such as PRM training center Split enables education for different health professionals at the same place and time, which provides opportunities for learning about competencies of other team members and development of future collaboration. Also, a uniform approach to education in rehabilitation medicine is provided for all health professionals. All of this sets a solid foundation for education of integrated rehabilitation team and achieving excellence in contemporary Croatian PRM. Implications for Rehabilitation In order to achieve high quality rehabilitation it is necessary to make education accessible to all rehabilitation team members. Implementation of rehabilitation principles in undergraduate education sets a good foundation for the development of postgraduate and specialty training in rehabilitation medicine. Academic setting such as physical and rehabilitation medicine training center Split provides a uniform approach to education in rehabilitation medicine for all health professionals.

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Health-Related Quality of Life Among Patients with Postmenopausal Osteoporosis Treated with Weekly and Monthly Bisphosphonates

Abstract: Conclusion: the study demonstrated that patients who were transferred from weekly bisphosphonates to a monthly ibandronate experienced improved HR-QoL.

Cited by 12 publications

References 25 publications

Evaluation of pain, quality of life, and patient satisfaction in parenterally treated patients with postmenopausal osteoporosis

Evaluation of pain, quality of life, and patient satisfaction in parenterally treated patients with postmenopausal osteoporosis

Clinical Effects of a 6-Month Treatment Course of Ibandronate, Vitamin D, and Calcium in Postmenopausal Women from Central America: Results of a Multinational, Prospective Pilot Study

Physical and rehabilitation medicine training center in Split, Croatia: striving to achieve excellence in education of a rehabilitation team

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