Headache Direction and Aura Predict Migraine Responsiveness to Rimabotulinumtoxin B

Abstract

Reported migraine directionality and presence of migrainous aura predict migraine headache responsiveness to rimabotulinumtoxin B injections.

Short and Mid‐Term Predictors of Response to OnabotulinumtoxinA: Real‐Life Experience Observational Study

“…At month 12 of treatment, a clinically significant excellent response was associated with earlier onset age of migraine, less years of evolution of migraine, presence of anxiety, and MWA. Our results are in line with those that found that the presence of symptoms such as allodynia or aura which are correlated with central mechanisms, a shorter disease duration and being younger subjects are factors of excellent response to preventive treatment with OnabotulinumtoxinA.…”

Short and Mid‐Term Predictors of Response to OnabotulinumtoxinA: Real‐Life Experience Observational Study

“…At month 12 of treatment, a clinically significant excellent response was associated with earlier onset age of migraine, less years of evolution of migraine, presence of anxiety, and MWA. Our results are in line with those that found that the presence of symptoms such as allodynia or aura which are correlated with central mechanisms, a shorter disease duration and being younger subjects are factors of excellent response to preventive treatment with OnabotulinumtoxinA.…”

The Efficacy of Botulinum Toxin Use in Service Members and Veterans with Migraine and Post-Traumatic Headache Disorders: A Scoping Review

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Imploding and Exploding Migraine Headaches: Comparison of Methods to Diagnose Pain Directionality

“…Responders were more likely to describe their headache as “imploding or ocular,” while nonresponders were more likely to describe “exploding” headache. Other studies looking at patient perception of migraine directionality as a predictor of responsiveness to onabotulinumtoxin treatment have shown similar results . The pathophysiology underlying the difference in these 2 groups is not clear, but it has been suggested that imploding or ocular headache may have an extracranial origin that is mediated by activation of meningeal nerves that infiltrate the periosteum through the calvarial sutures …”

Short and Mid‐Term Predictors of Response to OnabotulinumtoxinA: Real‐Life Experience Observational Study

“…At month 12 of treatment, a clinically significant excellent response was associated with earlier onset age of migraine, less years of evolution of migraine, presence of anxiety, and MWA. Our results are in line with those that found that the presence of symptoms such as allodynia or aura which are correlated with central mechanisms, a shorter disease duration and being younger subjects are factors of excellent response to preventive treatment with OnabotulinumtoxinA.…”

The Efficacy of Botulinum Toxin Use in Service Members and Veterans with Migraine and Post-Traumatic Headache Disorders: A Scoping Review

“……”

“……”

“……”

Imploding and Exploding Migraine Headaches: Comparison of Methods to Diagnose Pain Directionality

“…Responders were more likely to describe their headache as “imploding or ocular,” while nonresponders were more likely to describe “exploding” headache. Other studies looking at patient perception of migraine directionality as a predictor of responsiveness to onabotulinumtoxin treatment have shown similar results . The pathophysiology underlying the difference in these 2 groups is not clear, but it has been suggested that imploding or ocular headache may have an extracranial origin that is mediated by activation of meningeal nerves that infiltrate the periosteum through the calvarial sutures …”

Short and Mid‐Term Predictors of Response to OnabotulinumtoxinA: Real‐Life Experience Observational Study

“…At month 12 of treatment, a clinically significant excellent response was associated with earlier onset age of migraine, less years of evolution of migraine, presence of anxiety, and MWA. Our results are in line with those that found that the presence of symptoms such as allodynia or aura which are correlated with central mechanisms, a shorter disease duration and being younger subjects are factors of excellent response to preventive treatment with OnabotulinumtoxinA.…”

The Efficacy of Botulinum Toxin Use in Service Members and Veterans with Migraine and Post-Traumatic Headache Disorders: A Scoping Review

“……”

“……”

“……”

Imploding and Exploding Migraine Headaches: Comparison of Methods to Diagnose Pain Directionality

“…Responders were more likely to describe their headache as “imploding or ocular,” while nonresponders were more likely to describe “exploding” headache. Other studies looking at patient perception of migraine directionality as a predictor of responsiveness to onabotulinumtoxin treatment have shown similar results . The pathophysiology underlying the difference in these 2 groups is not clear, but it has been suggested that imploding or ocular headache may have an extracranial origin that is mediated by activation of meningeal nerves that infiltrate the periosteum through the calvarial sutures …”