Haplotype-aware multiomics unveils the regulatory basis of haplodiplontic life-cycle differentiation in a cosmopolitan marine alga
Tzu-Tong Kao,
Ming-Wei Lai,
Tzu-Haw Wang
et al.
Abstract:Gephyrocapsa huxleyi, a key coccolithophore alga influencing the global carbon cycle through photosynthesis and calcification, undergoes a haplodiplontic sexual life cycle with a calcifying non-flagellate diploid and a non-calcifying biflagellate haploid stage. To reveal the molecular basis of their morpho-physiological distinctions, we generated chromosome-level genome assemblies for a pair of isogenic haploid and diploid model strains and conducted haplotype-aware analyses of their multiomic features. In add… Show more
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