Hum Genet volume 84, issue 1, P66-70 1989 DOI: 10.1007/bf00210674 View full text
Eeva-Marja Sankila, Thomas Lehner, Aldur W. Eriksson, Henrik Forsius, Jussi Kärnä, David Page, Jürg Ott, Albert de la Chapelle

Abstract: Multipoint linkage analysis of choroideremia (TCD) and seven X chromosomal restriction fragment length polymorphisms (RFLPs) was carried out in 18 Finnish TCD families. The data place TCD distal to PGK and DXS72, very close to DXYS1 and DXYS5 (Zmax = 24 at theta = 0) and proximal to DXYS4 and DXYS12. This agrees with the data obtained from other linkage studies and from physical mapping. All the TCD males and carrier females studied have the same DXYS1 allele in coupling with TCD. In Northeastern Finland, 66/6…

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