Handgrip Strength and Its Associated Factors among Community-dwelling Elderly in Sri Lanka: A Cross-sectional Study

Damayanthi, Hewaratne Dassanayakege Wimala Thushari; Moy, Foong Ming; Abdullah, Khatijah Lim; Dharmaratne, Samath D

doi:10.1016/j.anr.2018.08.008

Cited by 15 publications

(30 citation statements)

References 28 publications

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“…Multivariable regression analysis was performed to examine the association between BCAA intake and handgrip strength. Potential confounding factors were selected through a comprehensive review of the preliminary analysis and included risk factors associated with handgrip strength and factors associated with BCAA intake [ 38 , 39 , 40 , 41 , 42 ]. The potential effect modification was examined using multiplicative terms of the statistical model, and no significant effect modifier was observed.…”

Section: Methodsmentioning

confidence: 99%

Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults

Park

Chae

Park³

et al. 2021

Nutrients

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Sarcopenia is a disease of old age characterized by decreased muscle mass and strength. Branched-chain amino acids (BCAAs) promote muscle mass synthesis and increase muscle strength. We aimed to develop a dietary amino acid database and to examine the association between BCAA intake and handgrip strength in Korean older adults. Data from the Korea National Health and Nutrition Examination Survey 2014–2018 were used. Overall, 4852 participants aged ≥65 years were included in the study. Demographic, lifestyle, and health data were obtained through interviews and questionnaires. The 24-h recall method was used to assess dietary intake. An amino acid database was established using the 9th revision of the Korean Standard Food Composition Table. The mean handgrip strength was estimated from triplicate measurements obtained using the dominant hand. Multivariable linear regression analysis was performed to assess the association between BCAA intake and handgrip strength. Grains greatly contributed to amino acid intake; however, a significant negative association was observed between handgrip strength and increased BCAA intake through grains. In the fully adjusted model, leucine intake and handgrip strength showed a positive association. Thus, consuming BCAAs (especially leucine) via a variety of food sources can help maintain muscle health in older people.

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Section: Methodsmentioning

confidence: 99%

Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults

Park

Chae

Park³

et al. 2021

Nutrients

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“…Indeed, the use of reference values from the target population is fundamental for the accurate interpretation of grip performance [15]. While many studies have established such normative values for older adults [16][17][18][19][20], there are fewer data available for middle-aged adult and young adult populations. Consequently, the potential to identify those with, or at risk of, low grip strength is greatly limited for these cohorts.…”

Section: Introductionmentioning

confidence: 99%

Grip strength performance from 9431 participants of the GenoFit study: normative data and associated factors

et al. 2021

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Weak grip strength is a strong predictor of multiple adverse health outcomes and an integral diagnostic component of sarcopenia. However, the limited availability of normative data for certain populations impedes the interpretation of grip performance across adulthood. This study aimed to establish normative data and low grip strength thresholds in a large adult population, and to examine associations between grip strength and clinically relevant health variables. A total of 9431 adults aged between 18 and 92 years participated in this study (mean age: 44.8 ± 13.4 years; 57% females). Grip strength, body composition, and cardiorespiratory (CR) fitness were assessed using hand dynamometry, dual-energy x-ray absorptiometry and physical work capacity tests, respectively. Low grip strength was established according to criteria of the European Working Group on Sarcopenia in Older People. Normative data and t-scores, stratified by sex and age groups, are presented. Grip performance was associated with lean mass, skeletal muscle index (SMI), fat mass, CR fitness, bone mineral density (BMD), android/gynoid ratio, disease prevalence and physical activity levels (all p < 0.001) after controlling for multiple potential confounders. Individuals with weak grip strength had lower lean mass, SMI, CR fitness (all p < 0.001) and BMD (p = 0.001), and higher disease prevalence (p < 0.001), compared to healthy controls, although sex-specific differences were observed. Grip strength has practical screening utility across a range of health domains. The normative data and grip strength thresholds established in this study can guide the clinical interpretation of grip performance and facilitate timely therapeutic strategies targeting sarcopenia.

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“…A significant association between osteoporosis and muscle strength, however, has been observed [ 48 ] in PMW, previously. This could be due to the fact that the risk factors of osteoporosis and sarcopenia, including age, genetics, endocrine function, and mechanical factors are similar [ 49 – 51 ].…”

Section: Discussionmentioning

confidence: 99%

Factors associated with measures of sarcopenia in pre and postmenopausal women

et al. 2021

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Background Menopause associated low serum estradiol marks varieties of derangements in muscle mass and functions leading to sarcopenia. This cross-sectional study was carried out to examine the factors associated with measures of sarcopenia; skeletal muscle mass (SMM), muscle strength and physical performance (PP) in a group of premenopausal (PrMW) and postmenopausal women (PMW) selected from Sri Lanka. Methods Randomly selected 184 PrMW and 166 PMW from Galle district, Sri Lanka were studied. SMM was measured with duel energy X ray absorptiometry and relative appendicular SMM index (RSMI; kg/m2) was calculated. Other measurements made include handgrip strength (HGS; kg) and gait speed (GS; m/s), anthropometric indices, consumption of macro and micronutrients, and pattern of physical activities (PA). A serum sample was analyzed for fasting insulin, serum estradiol and vitamin D. Variables which significantly correlated with RSMI, HGS and GS of PrMW and PMW were separately entered into multiple linear regression models to extract the associated factors. Results Mean (SD) age of PrMW and PMW were 42.4 (6.0) and 55.8 (3.8) years respectively. In the regression analysis, RSMI in PrMW showed significant associations with body mass index (BMI), HGS, total-body-fat-mass (TBFM) and weight (adjusted R2 = 0.85) and in PMW with BMI, weight, TBFM, hip-circumference and fasting insulin (adjusted R2 = 0.80). BMI showed the strongest association with RSMI in both PrMW (r = 0.87, R2 = 0.76) and in PMW (r = 0.87, R2 = 0.76). HGS in PrMW showed significant associations with appendicular SMM (ASMM), total-body-bone-mineral-content, vigorous PA score, age and weight (adjusted R2 = 0.33) and in PMW with ASMM and height (adjusted R2 = 0.23). ASMM showed the strongest association with HGS in both PrMW (r = 0.44, R2 = 0.20) and PMW (r = 0.44, R2 = 0.20). GS in PrMW showed significant associations with height, BMI and energy consumption (adjusted R2 = 0.13) while in PMW, with carbohydrate consumption and total-body-bone-mineral-density (adjusted R2 = 0.09). While in PrMW, height showed the strongest association with GS (r = 0.28, R2 = 0.08) in PMW, it was carbohydrate consumption (r = 0.24, R2 = 0.06). Conclusions Factors that are associated with different measures of sarcopenia are not uniform and vary widely from anthropometry to nutrient intake indicating that these measures are somewhat independent and are governed by different factors.

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Handgrip Strength and Its Associated Factors among Community-dwelling Elderly in Sri Lanka: A Cross-sectional Study

Cited by 15 publications

References 28 publications

Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults

Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults

Grip strength performance from 9431 participants of the GenoFit study: normative data and associated factors

Factors associated with measures of sarcopenia in pre and postmenopausal women

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