Hand Radiological Damage in Systemic Sclerosis: Comparison with a Control Group and Clinical and Functional Correlations

A comparative study between ultrasonographic hand features in systemic sclerosis and rheumatoid arthritis patients: Relation to disease activity, clinical and radiological findings

“…In our study, US in SSc patients showed a significantly higher number of joints with osteophytes than X-rays (p = 0.004) with only one patient showing erosions by US, while in RA US showed a higher number of joints with joint space narrowing and erosions than X-rays. These results are consistent with published data [19,6]. In another Egyptian study on SSc patients, hand disability was mainly related to impaired hand mobility and also diminished strength.…”

“…Radiographic studies in SSc and RA have shown that the commonly affected areas are the joints, soft tissue, and bones of the hands [13,14,[17][18][19]. However, radiographs exhibit some limitations regarding their sensitivity to detect early inflammatory changes, such as effusion or synovitis, and they cannot assess tendon damage.…”

Acroosteolysis in systemic sclerosis: An insight into hypoxia-related pathogenesis

“…Acroosteolysis (AO), a distinct pattern of bone resorption affecting the distal portion of the fingers, which occurs in 6-65% of patients with SSc, is an incompletely addressed feature of the disease that contributes to disability and pain (2)(3)(4)(5)(6).…”

Acroosteolysis of distal phalanges in patient with systemic sclerosis – case report

“…wykazali znamienną korelację pomiędzy późną fazą klasyfikacji zmian kapilaroskopowych wg Cutolo a występowaniem wapnienia w obrębie tkanek bądź osteolizy [8,9]. Uważa się, że akroosteoliza może być skutkiem niedostatecznego ukrwienia, a także może mieć związek z uciskiem wywołanym włóknieniem otaczających tkanek [10]. Johnstone i wsp.…”