Hamartoma of the Skin

Way, Stuart C.

doi:10.1038/jid.1948.25

Cited by 5 publications

(2 citation statements)

References 7 publications

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“…In 1904, Albrecht used the word hamartoma for a tumor that developed due to overdevelopment of some kind of tissue, which normally belonged at the site where it was formed or to any abnormal relationship of a normally situated tissue element. [ 2 ] They are cell nests or collection of abnormal number of normal cells that can be epidermal or dermal—sebaceous, apocrine, or eccrine.…”

Section: Discussionmentioning

confidence: 99%

Apocrine hidrocystoma arising from nevus sebaceous on the scalp

Tejaswi

Rangaraj

Karthikeyan

2016

Indian Dermatol Online J

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Nevus sebaceous is a hamartoma with an uneventful course since birth but many benign or malignant tumors are known to develop in about one third of the patients. A 37-year-old woman with asymptomatic hairless raised lesion over the scalp since birth presented with change in the morphology of the lesions associated with itching and irritation since one month. On examination, multiple well-defined hyperpigmented verrucous plaques coalescing with each other were seen over the right parietal scalp associated with alopecia. A single well-defined soft skin-colored cystic swelling of size 1 × 2 cm was seen interspersed within the plaque. After a clinical diagnosis of nevus sebaceous, a biopsy of the cyst was done, which revealed a large cyst lined by columnar and myoepithelial cells in the dermis. The columnar cells at a few places showed “decapitation secretion” giving the impression of apocrine hidrocystoma. Post-excision of the cyst, biopsy of the entire nevus was done and the histopathological diagnosis correlated with the clinical diagnosis of nevus sebaceous. Apocrine hidrocystoma developing from a sebaceous nevus over the scalp is a rarity with only three other cases of it arising on the scalp being reported and none of them developed from a sebaceous nevus.

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Section: Discussionmentioning

confidence: 99%

Apocrine hidrocystoma arising from nevus sebaceous on the scalp

Tejaswi

Rangaraj

Karthikeyan

2016

Indian Dermatol Online J

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“…Our case was interesting in that the age of onset was 70 years and its location was on the forehead. The typical sites of EAH are the distal extremities, with the neck, 2 chest, 4 back, 5 and sacral region 6 rarely involved. After an extensive review of the literature, no report on this location could be found.…”

Section: Discussionmentioning

confidence: 99%

Late‐onset eccrine angiomatous hamartoma on the forehead

Jeong

Park

et al. 2004

Int J Dermatology

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A 71-year-old Korean man presented with a solitary erythematous plaque on his forehead (Fig. 1). It was first noticed by the patient 1 year previously and had slowly increased in size over that time. Physical examination revealed a slightly elevated, 1.5 cm x 1.5 cm erythematous plaque on the upper midline of the forehead. Sweating was not evoked by physical work or emotional stress. There was no pain or tenderness associated with the lesion. The patient had no history of trauma to the forehead. Histopathologic examination of the lesion showed increased numbers of eccrine glands, as well as dilated vascular channels in the deep dermis and subcutaneous tissue (Fig. 2). An immunohistochemical study showed that these eccrine glands stained positively for S-100 and carcinoembryonic antigen (CEA), and the vascular channels for the antifactor VIII-related antigens. These findings are consistent with eccrine angiomatous hamartoma. There was no change in the lesion during the 1-year follow-up period.

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Hamartoma angiomatoso ecrino

Vázquez

Calle

2004

Piel

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Hamartoma of the Skin

Cited by 5 publications

References 7 publications

Apocrine hidrocystoma arising from nevus sebaceous on the scalp

Apocrine hidrocystoma arising from nevus sebaceous on the scalp

Late‐onset eccrine angiomatous hamartoma on the forehead

Hamartoma angiomatoso ecrino

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