Hallermann-Streiff Syndrome

Mandibulo-oculo-facial dyscephaly.

“…The present case shows a complete absence of the lens in both eyes. Falls and Schull (1960) have reported the spontaneous rupture and absorption of the cataractous lens in two of their cases, but in the present case there was no evidence of any capsular remnants or shreds on slit-lamp examination and the pupillary area was perfectly clear. There was no history of any eye operation, the patient's vision being the same from the very beginning.…”

“…In one case only (Falls and Schull, 1960) was there a clear history of exposure to measles in the first trimester, but the mother did not suffer from any disease during pregnancy and she had had rubella previously. Therefore in this case, too, there is no conclusive evidence to show that any exogenous aetiological agent is in any way related to this syndrome.…”

“…The fact that most of these patients remained unmarried because of their unattractive physical appearance and that none of them had any offspring does not totally exclude this factor. Frangois (1958) and Ullrich and Fremerey-Dohna (1953) have suggested that it may be either a recessive affection or a mutation. Falls and Schull (1960) consider recessive affection as unlikely in view of the sporadic occurrence and the total absence of consanguineous marriages amongst the patients reported.…”

Mandibulo-oculo-facial dyscephaly.

“…The present case shows a complete absence of the lens in both eyes. Falls and Schull (1960) have reported the spontaneous rupture and absorption of the cataractous lens in two of their cases, but in the present case there was no evidence of any capsular remnants or shreds on slit-lamp examination and the pupillary area was perfectly clear. There was no history of any eye operation, the patient's vision being the same from the very beginning.…”

“…In one case only (Falls and Schull, 1960) was there a clear history of exposure to measles in the first trimester, but the mother did not suffer from any disease during pregnancy and she had had rubella previously. Therefore in this case, too, there is no conclusive evidence to show that any exogenous aetiological agent is in any way related to this syndrome.…”

“…The fact that most of these patients remained unmarried because of their unattractive physical appearance and that none of them had any offspring does not totally exclude this factor. Frangois (1958) and Ullrich and Fremerey-Dohna (1953) have suggested that it may be either a recessive affection or a mutation. Falls and Schull (1960) consider recessive affection as unlikely in view of the sporadic occurrence and the total absence of consanguineous marriages amongst the patients reported.…”

Spontaneous absorption of a cataractous lens

“…Spontaneous absorption of the lens material in an adult may be seen in the end stage of cataract formation. It has been reported to occur in children with Hallerman-Streiff syndrome (Francois 1958;Falls & Schull 1960). The eyes are usually small and contain cataracts that characteristically undergo spontaneous absorption.…”

Pediatric cataract: challenges and future directions

“……”

Mandibulo-oculo-facial dyscephaly.

“…The present case shows a complete absence of the lens in both eyes. Falls and Schull (1960) have reported the spontaneous rupture and absorption of the cataractous lens in two of their cases, but in the present case there was no evidence of any capsular remnants or shreds on slit-lamp examination and the pupillary area was perfectly clear. There was no history of any eye operation, the patient's vision being the same from the very beginning.…”

“…In one case only (Falls and Schull, 1960) was there a clear history of exposure to measles in the first trimester, but the mother did not suffer from any disease during pregnancy and she had had rubella previously. Therefore in this case, too, there is no conclusive evidence to show that any exogenous aetiological agent is in any way related to this syndrome.…”

“…The fact that most of these patients remained unmarried because of their unattractive physical appearance and that none of them had any offspring does not totally exclude this factor. Frangois (1958) and Ullrich and Fremerey-Dohna (1953) have suggested that it may be either a recessive affection or a mutation. Falls and Schull (1960) consider recessive affection as unlikely in view of the sporadic occurrence and the total absence of consanguineous marriages amongst the patients reported.…”

Spontaneous absorption of a cataractous lens

“…Spontaneous absorption of the lens material in an adult may be seen in the end stage of cataract formation. It has been reported to occur in children with Hallerman-Streiff syndrome (Francois 1958;Falls & Schull 1960). The eyes are usually small and contain cataracts that characteristically undergo spontaneous absorption.…”

Pediatric cataract: challenges and future directions

“……”

Mandibulo-oculo-facial dyscephaly.

“…The present case shows a complete absence of the lens in both eyes. Falls and Schull (1960) have reported the spontaneous rupture and absorption of the cataractous lens in two of their cases, but in the present case there was no evidence of any capsular remnants or shreds on slit-lamp examination and the pupillary area was perfectly clear. There was no history of any eye operation, the patient's vision being the same from the very beginning.…”

“…In one case only (Falls and Schull, 1960) was there a clear history of exposure to measles in the first trimester, but the mother did not suffer from any disease during pregnancy and she had had rubella previously. Therefore in this case, too, there is no conclusive evidence to show that any exogenous aetiological agent is in any way related to this syndrome.…”

“…The fact that most of these patients remained unmarried because of their unattractive physical appearance and that none of them had any offspring does not totally exclude this factor. Frangois (1958) and Ullrich and Fremerey-Dohna (1953) have suggested that it may be either a recessive affection or a mutation. Falls and Schull (1960) consider recessive affection as unlikely in view of the sporadic occurrence and the total absence of consanguineous marriages amongst the patients reported.…”

Spontaneous absorption of a cataractous lens

“…Spontaneous absorption of the lens material in an adult may be seen in the end stage of cataract formation. It has been reported to occur in children with Hallerman-Streiff syndrome (Francois 1958;Falls & Schull 1960). The eyes are usually small and contain cataracts that characteristically undergo spontaneous absorption.…”

Pediatric cataract: challenges and future directions

“……”