“…13 Furthermore, recent studies in other patient groups have largely failed to show a significant prophylactic effect of retinoids against BCCs. [1][2][3]17 Dermabrasion has also been shown to decrease the number of future actinic keratoses 1-3 and even the number of future skin cancers in patients with severe actinic damage, 1,2 or xeroderma pigmentosum. [1][2][3]17 Dermabrasion has also been shown to decrease the number of future actinic keratoses 1-3 and even the number of future skin cancers in patients with severe actinic damage, 1,2 or xeroderma pigmentosum.…”
Section: Discussionmentioning
confidence: 99%
“…[1][2][3] We believe that CO 2 laser resurfacing can have the same therapeutic benefits as dermabrasion while allowing for more precision and a relatively bloodless field. [1][2][3] We believe that CO 2 laser resurfacing can have the same therapeutic benefits as dermabrasion while allowing for more precision and a relatively bloodless field.…”
“…13 Furthermore, recent studies in other patient groups have largely failed to show a significant prophylactic effect of retinoids against BCCs. [1][2][3]17 Dermabrasion has also been shown to decrease the number of future actinic keratoses 1-3 and even the number of future skin cancers in patients with severe actinic damage, 1,2 or xeroderma pigmentosum. [1][2][3]17 Dermabrasion has also been shown to decrease the number of future actinic keratoses 1-3 and even the number of future skin cancers in patients with severe actinic damage, 1,2 or xeroderma pigmentosum.…”
Section: Discussionmentioning
confidence: 99%
“…[1][2][3] We believe that CO 2 laser resurfacing can have the same therapeutic benefits as dermabrasion while allowing for more precision and a relatively bloodless field. [1][2][3] We believe that CO 2 laser resurfacing can have the same therapeutic benefits as dermabrasion while allowing for more precision and a relatively bloodless field.…”
“…Interestingly, in 1963 Burks, Marascalco, and Clark reported a similar histologic description after dermabrasion to severely sun‐damaged skin done for the prophylaxsis of actinic keratoses. They felt that hypopigmentation following dermabrasion may be due to a failure in melanin transfer 10 …”
This patient experienced a profound expression of an increasingly recognized and reported complication of carbon dioxide laser resurfacing. Histologic correlation is similar to the results previously reported after phenol chemical peels, demonstrating a normal number of melanocytes but a decrease in epidermal melanin.
“…This has been referred to as ''alabaster white'' skin. 7 Burks et al 8 also describe a similar hypopigmentation after dermabrasion. More recently, hypopigmentation has become a recognized side effect of laser resurfacing.…”
It is possible with skin preconditioning, LACA, and occlusive wound healing to provide for a wound healing environment that blends in areas of hypopigmentation that have developed after previous skin resurfacing.
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