Hailey-Hailey disease. Eradication by dermabrasion

Efficacy of Erbium:YAG Laser Ablation in Darier Disease and Hailey-Hailey Disease

“…[1][2][3] Good results for both diseases were obtained from such surgical interventions as excision 6,7 or excision with subsequent split-thickness skin grafting, 8 electrodesiccation, 9 and dermabrasion. [10][11][12][13][14] According to the observations of other authors, our own experiences have confirmed the value of dermabrasion, particulary in the treatment of HHD. However, DD frequently requires selective removal of keratotic papules and circumscribed deeper ablation in follicular lesions, which is not feasible with dermabrasion.…”

Frozen Human Epidermal Allogeneic Cultures Promote Rapid Healing of Facial Dermabrasion Wounds

“…Healing was judged to have taken place when removal of the gauze backing of the frozen cultures or the control dressing produced no bleeding. 9 Based on previously published reports using various moist dressings for acute wounds, including dermabrasion, chemical peel, and laser skin resurfacing in which complete reepithelization took longer than 7 days, 9,37,46–48 we conclude that our frozen cultured human epidermal allogenic sheets promoted significantly more rapid healing than any form of dressing alone, with a mean time of 4.6 days. Laser resurfacing of the skin produces a wound not very different from that of dermabrasion and should benefit equally from the use of frozen epidermal cultures.…”

A Rare Clinical Presentation of Intraoral Darier's Disease

“…However, the attempts at genotype-phenotype correlation have not been successful. Family members with confirmed identical ATP2A2 mutations can exhibit differences in the clinical severity of disease, suggesting that other genes or environmental factors affect the expression of keratosis follicularis [13, 14]. The present patient had white patches on perioral region mostly on the lips.…”