H. pylori induces MHC class II antigens expression and maturation of human plasmacytoid dendritic cells

Circulating plasmacytoid dendritic cells in patients with primary and Helicobacter pylori‐associated immune thrombocytopenia

“…Indeed, pDC number was persistently low in non‐responders after successful eradication of H. pylori in this study, even though the number of cases was small. Although little has been reported on the relationship between pDCs and H. pylori infection, pDCs may be induced to maturation and antigen presentation for the accumulating mDCs in H. pylori gastritis (51, 52). However, we cannot yet clarify how pDCs are involved in the pathogenesis of H. pylori ‐associated ITP.…”