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Cited by 165 publications
(149 citation statements)
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References 110 publications
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“…IVIg | sialylation | antibody | inflammation | autoimmune disease I ntravenous immunoglobulin (IVIg) is a therapeutic blood product prepared from the pooled plasma of 3,000-60,000 healthy donors per batch (1)(2)(3). It is a complex heterogeneous mixture of IgG subclasses and low amounts of IgA, IgM, and other plasma proteins (4).…”
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confidence: 99%
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“…IVIg | sialylation | antibody | inflammation | autoimmune disease I ntravenous immunoglobulin (IVIg) is a therapeutic blood product prepared from the pooled plasma of 3,000-60,000 healthy donors per batch (1)(2)(3). It is a complex heterogeneous mixture of IgG subclasses and low amounts of IgA, IgM, and other plasma proteins (4).…”
mentioning
confidence: 99%
“…IVIg has been used for more than 30 years for the treatment of a variety of acute and chronic autoimmune and systemic inflammatory diseases (2)(3)(4)(5). Although efficacious in these diseases, the precise mechanism of action of IVIg is not well-understood.…”
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confidence: 99%
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“…[6][7][8][9][10][11][12] These sources are useful in evaluating Ig because the expert opinion and consensus provide balanced evidence assessments. Referencing these publications, we defined the following levels of evidence: "supported," "conditional," "lacking consensus," "currently not supported," and "undetermined."…”
Section: Review Of Published Evidencementioning
confidence: 99%
“…Other sources used, such as the guidelines by Feasby et al 6 and Anderson et al (2007), 9 provided more specific recommendations, suggesting that Ig should be considered only after other first-line agents have been tried and failed or are otherwise contraindicated. This scenario was also categorized as "conditional."…”
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confidence: 99%