Guidelines on Testicular Cancer: 2015 Update

Albers, Peter; Albrecht, Walter; Algaba, Ferrán; Bokemeyer, Carsten; Cohn‐Cedermark, Gabriella; Fizazi, Karim; Horwich, A.; Laguna, M. Pilar; Nicolai, Nicola; Oldenburg, Jan

doi:10.1016/j.eururo.2015.07.044

Cited by 590 publications

(640 citation statements)

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“…A testicular yolk sac tumor is a type of NSGCT (1,3). Testicular yolk sac tumors are common in children exhibiting testicular cancer, however, they are rarely observed in adults (4).…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, the incidence of testicular cancer has increased, particularly in industrialized countries (1). For example, in the USA, the incidence of testicular germ cell tumors increased from 5.7 to 6.8 cases per 100,000 individuals between 1992 and 2009 (1,2).…”

Section: Introductionmentioning

confidence: 99%

“…For example, in the USA, the incidence of testicular germ cell tumors increased from 5.7 to 6.8 cases per 100,000 individuals between 1992 and 2009 (1,2). Testicular yolk sac tumors are a type of non-seminomatous germ cell tumor (NSGCT) (1,3). Testicular pure yolk sac tumors are rare in adults (4).…”

Section: Introductionmentioning

confidence: 99%

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Adult metastatic yolk sac tumor descending from an intra-abdominal testis: A case report and review of the literature

et al. 2015

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Abstract. Pure yolk sac tumors are extremely rare in adults; to the best of our knowledge, <20 cases have been reported. Multiple metastases originating from a pure yolk sac testicular tumor, descending from an intra-abdominal testis, are additionally extremely rare. In the present case, a man exhibiting a 30-year history of cryptorchidism and indirect inguinal hernia, was admitted to the Department of Urology (The Second Xiangya Hospital, Changsha, China) due to a mass that had descended from the abdominal cavity 7 months previously. Elevated levels of specific serum marker (α-fetoprotein, lactate dehydrogenase and human chorionic gonadotropin ) did not indicate potential testicular germ cell types prior to surgery and pathological examination. Pathological results and immunohistochemistry revealed a testicular pure yolk sac tumor subsequent to surgery. The present case report and literature review describes the typical characteristics of an adult testicular yolk sac tumor, as well as the diagnosis and management of the disease.

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“…A testicular yolk sac tumor is a type of NSGCT (1,3). Testicular yolk sac tumors are common in children exhibiting testicular cancer, however, they are rarely observed in adults (4).…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Adult metastatic yolk sac tumor descending from an intra-abdominal testis: A case report and review of the literature

et al. 2015

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“…All men diagnosed with stage 1 disease will survive for five years or more, compared to 80% of those diagnosed with advanced disease. 2,3 A NEW LUMP IN THE TESTIS TC will typically present as a hard, painless lump noticed on self-examination ( Figure 1). The history should enquire about duration of the lump, pain, risk factors for TC and sexual activity.…”

Section: Wwwtrendsinmenshealthcom Trends In Urology and Men's Health mentioning

confidence: 99%

“…Enucleation of the mass, followed by histopathological frozen section from the resection margins, can guide as to whether the lesion is benign or malignant and whether further resection or orchidectomy is necessary. 3,12 PATHOLOGY Germ cell tumours (GCTs) account for 95% of TCs, half of which are seminomas; the other half are non-seminomatous germ cell tumours (NSGCTs). Seminomas tend to occur in a higher age group (peak age 30-45 years) than NSGCTs (peak age 20-35 years).…”

Section: Managementmentioning

confidence: 99%