Guidelines on Asbestos-Related Pleuropulmonary Disease

Montes, Isabel Isidro; Shams, Khalil Abu; Alday, E.; Sastre, J.L. Carretero; Sancho, Jaume Ferrer; Blanxart, Alberto; Molas, Eduard Monsó; Martínez, I. Pascal; Becerra, E. Rodríguez; Panadero, Francisco Rodríguez

doi:10.1016/s1579-2129(06)60416-3

Cited by 20 publications

(6 citation statements)

References 61 publications

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“…Asbestos toxicity is related to its fibrous structure, since studies have demonstrated that pulverized asbestos does not cause disease [7]. Due to individual susceptibility factors, the development of ARD cannot be ruled out in individuals with low intensity exposure to asbestos [8,9].…”

Section: Introductionmentioning

confidence: 99%

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Risk factors associated with asbestos-related diseases: a community-based case–control study

Rosell‐Murphy

Abós‐Herràndiz²,

Olivella³

et al. 2013

BMC Public Health

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BackgroundAsbestos is a first level carcinogen. However, few epidemiological studies analyse the risk and protective factors associated with asbestos-related diseases and follow up these conditions in the general population. Pleural mesothelioma, caused by inhalation of asbestos fibres at work, at home or in the environment, is the most representative asbestos-related disease.The objectives of this study are to analyse the risk and protective factors associated with asbestos-related diseases and to investigate the incidence of new clinical manifestations in patients already diagnosed with some form of ARD.Methods/DesignWe have designed a matched case–control study with follow up of both cohorts from a population of a health district of the Barcelona province that has been exposed to asbestos for a period of 90 years.DiscussionA better understanding of asbestos-related diseases should improve i) the clinical and epidemiological follow up of patients with this condition; ii) the design of new treatment strategies; iii) and the development of preventive activities. At the end of the study, the two cohorts created in this study (affected cases and healthy controls) will constitute the basis for future research.

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Section: Introductionmentioning

confidence: 99%

“…However, this figure has been now reviewed and increased to 3 new cases/million inhabitants/year [7]. In the province of Barcelona, the incidence of mesothelioma estimated from mortality data of residents equals 8.3 cases/million inhabitants/year in men, and 4.7 cases/million inhabitants/year in women.…”

Section: Introductionmentioning

confidence: 99%

Risk factors associated with asbestos-related diseases: a community-based case–control study

Rosell‐Murphy

Abós‐Herràndiz²,

Olivella³

et al. 2013

BMC Public Health

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“…Asbestos toxicity is related to its fibrous structure, since it has been shown that pulverized asbestos does not cause disease [6]. Short or low intensity exposure to asbestos does not exclude the possibility of ARD, since there are individual susceptibility factors to asbestosis still poorly understood [7].…”

Section: Introductionmentioning

confidence: 99%

“…The imaging techniques can show a diffuse thickening of the pleura (mainly visceral), pleural plaques (mainly parietal, calcified or not calcified), massive or partial pleural effusion, pleural masses and even a bibasilar honeycombing pattern, characteristic of pulmonary fibrosis [6]. The high-resolution CT scan is more accurate and sensitive than conventional X-ray and conventional CT scan, which has a low predictive value of 50%.…”

Section: Introductionmentioning

confidence: 99%

“…It is accepted that the "spontaneous" incidence of mesothelioma is extremely rare, less than 1 new case for one million inhabitants per year [20]. In Western Europe the incidence was around 1 per million until the middle of the 1950s, but currently it has increased to 3 per million per year [6]. No data on the incidence of non-malignant ARD exist.…”

Section: Introductionmentioning

confidence: 99%

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Prospective study of asbestos-related diseases incidence cases in primary health care in an area of Barcelona province

et al. 2010

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BackgroundAsbestos related diseases include a number of conditions due to inhalation of asbestos fibres at work, at home or in the environment, such as pleural mesothelioma, asbestosis and calcified pleural plaques. Few epidemiological studies have established the incidence of asbestos related diseases in our area. The present proposal is based on a retrospective study externally funded in 2005 that is currently taking place in the same area and largely carried out by the same research team.The aim of the study is to achieve a comprehensive and coordinated detection of all new cases of Asbestos Related Diseases presenting to primary care practitioners.Methods/designThis is a multicentre, multidisciplinary and pluri-institutional prospective study.Setting12 municipalities in the Barcelona province within the catchment area of the health facilities that participate in the study.SampleThis is a population based study, of all patients presenting with diseases caused by asbestos in the study area.MeasurementsA clinical and epidemiological questionnaire will be filled in by the trained researchers after interviewing the patients and examining their clinical reports.DiscussionData on the incidence of the different Asbestos Related Diseases in this area will be obtained and the most plausible exposure source and space-time-patient profile will be described. The study will also improve the standardization of patient management, the coordination between health care institutions and the development of preventive activities related with asbestos exposure and disease.

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