Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report

Boyce, Joshua A.; Assa’ad, Amal; Burks, A. Wesley; Jones, Stacie M.; Sampson, Hugh A.; Wood, Robert A.; Plaut, Marshall; Cooper, Susan; Fenton, Matthew J.; Arshad, Syed Hasan; Bahna, Sami L.; Beck, Lisa A.; Byrd‐Bredbenner, Carol; Camargo, Carlos A.; Eichenfield, Lawrence F.; Furuta, Glenn T.; Hanifin, Jon M.; Jones, Caleb; Kraft, Monica; Levy, Bruce D.; Lieberman, Phil; Luccioli, Stefano; McCall, Kathleen M.; Schneider, Lynda C.; Simon, Ronald A.; Simons, F. Estelle R.; Teach, Stephen J.; Yawn, Barbara P.; Schwaninger, Julie M.

doi:10.1016/j.jaad.2010.11.020

Cited by 177 publications

(204 citation statements)

References 1 publication

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“…In infants with persistent wheezing despite treatment with bronchodilators, inhaled corticosteroids, or systemic corticosteroids, we recommend research studies that compare clinical outcomes among infants who are managed according to infant PFT performed using the RVRTC technique versus those who are managed according to clinical assessment alone. (76). Therefore, we focused our question on the role of food avoidance in infants without eczema.…”

Section: American Thoracic Society Documentsmentioning

confidence: 99%

Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing

Ren¹,

Esther²,

Debley³

et al. 2016

Am J Respir Crit Care Med

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Although infantile wheezing is common, there is a paucity of evidence to guide clinicians in selecting diagnostic tests for recurrent or persistent wheezing. Our committee made several conditional recommendations to guide clinicians; however, additional research that measures clinical outcomes is needed to improve our confidence in the effects of various diagnostic interventions and to allow advice to be provided with greater confidence.

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Section: American Thoracic Society Documentsmentioning

confidence: 99%

Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing

Ren¹,

Esther²,

Debley³

et al. 2016

Am J Respir Crit Care Med

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“…An expert panel set up for publishing guidelines for AD reviewed the literature and found that multiple studies demonstrated 50%–90% of presumed food allergy are not allergies. [23] Many patients may have sensitization but may not develop symptoms. Diagnoses of IgE-mediated reactions require sensitization and development of symptoms.…”

Section: Diagnosismentioning

confidence: 99%

Food allergy in atopic dermatitis

Dhar

Srinivas

2016

Indian J Dermatol

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Food allergy in atopic dermatitis (AD) is debatable from decades. Role of diet in the cause and treatment of AD is controversial and is not well-defined. Allergists and pediatricians are convinced about the food allergy in AD whereas many dermatologists are contrary for this. However, there are studies in the Indian and western literature supporting the evidence that elimination diet may improve the severe type of AD. There is increasing awareness and lot of misconception among caregivers about food allergy and hence careful understanding about this concept is necessary to counsel parents. Recent evidence-based literature suggests avoidance of proven food allergens in AD could be beneficial in moderate to severe type of AD.

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“…However, when tolerance is compromised and T h 2-type immune responses are induced to food antigens, IgE-mediated anaphylaxis, namely food allergy, can be evoked (1,2). Currently, the management of food allergy is achieved by allergen avoidance and prompt use of selfinjectable epinephrine in emergency cases (1,2,5). These measures significantly compromise patient quality of life and cannot completely avoid the threat of food allergy.…”

Section: Introductionmentioning

confidence: 99%

The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy

Muto

Fukuoka

Kabashima

et al. 2014

International Immunology

106

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Cutaneous sensitization with a food antigen before its consumption elicits the development of food allergy. Here, we report the site- and stage-dependent roles of basophils and proallergic cytokines, thymic stromal lymphopoietin (TSLP) and IL-33, in a mouse model of food allergy initially sensitized cutaneously with the food antigen. Mice were epicutaneously sensitized with the food antigen ovalbumin (OVA) followed by oral challenge with OVA. Epicutaneously sensitized mice produced OVA-specific IgE and developed IgE-dependent anaphylaxis after oral challenge. Basophil-depleted or TSLP-receptor-deficient mice did not produce OVA-specific IgE and were protected from oral challenge-induced anaphylaxis. IL-33-deficient mice produced normal levels of OVA-specific IgE. However, IL-33-deficient mice and mice treated with recombinant soluble IL-33 receptor were protected from anaphylaxis. Thus, basophils and TSLP have pivotal roles in Th2 development in the skin during the sensitization phase of food allergy. In contrast, while IL-33 is dispensable for promoting cutaneous antigen sensitization, the cytokine is essential for inducing IgE-dependent anaphylaxis in the gut.

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Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report

Cited by 177 publications

References 1 publication

Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing

Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing

Food allergy in atopic dermatitis

The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy

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