Animal Cell Culture and Production of Biologicals 1991
DOI: 10.1007/978-94-011-3550-4_50
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“…The antisense ODNs were strategically designed near the translation initiation codon, the sequence known empirically to be most effective in inhibiting translation of target mRNA (46). Previous studies have shown that short ODNs diffuse into mammalian cells, hybridize to target transcripts, and effectively degrade mRNA without any 2 Y. Ito and Y. Chai, unpublished data.…”
Section: The Level Of Smad Expression and Tooth Developmentmentioning
confidence: 99%