Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002)

Abstract

The British Society of Gastroenterology (BSG) and the Association of Coloproctology for Great Britain and Ireland (ACPGBI) commissioned this update of the 2002 guidance. The aim, as before, is to provide guidance on the appropriateness, method and frequency of screening for people at moderate and high risk from colorectal cancer. This guidance provides some new recommendations for those with inflammatory bowel disease and for those at moderate risk resulting from a family history of colorectal cancer. In other areas guidance is relatively unchanged, but the recent literature was reviewed and is included where appropriate.

miR-194 as a Predictor for Adenoma Recurrence in Patients with Advanced Colorectal Adenoma after Polypectomy

“…According to European guidelines (19), three or more adenomas with at least one >1 cm in size detected at any single examination indicate high risk and an extra examination should be undertaken at 12 months before returning to 3-yearly surveillance colonoscopies. In our study, 374 patients completed surveillance colonoscopy, in which 33 patients had more than three adenomas with at least one >1 cm.…”

The risks of cancer after bladder replacement or diversion

“…Flexible sigmoidoscopy is recommended annually from the twelfth year. 8 As a result, virtually all tumours are found at a benign stage and can be managed with local excision, assuming that the patient wants to continue with a U/sig.…”

Colonoscopic surveillance – a cost-effective method to prevent hereditary and familial colorectal cancer

“…Colonoscopic surveillance is a well-established method [1,2,5,6] for HCRC and FCRC prevention, although the scientific evidence on how to design an optimal surveillance programme is limited. There are different opinions and guidelines on how extensive a familial clustering of CRC must be to justify surveillance, at what age to start surveillance, and the length of examination intervals [5][6][7][8][9][10].…”

“…There are different opinions and guidelines on how extensive a familial clustering of CRC must be to justify surveillance, at what age to start surveillance, and the length of examination intervals [5][6][7][8][9][10].…”