Guideline for Management of Vasculitis Syndrome (JCS 2008) - Digest Version -

Group, JCS Joint Working

doi:10.1253/circj.cj-88-0007

Cited by 145 publications

(39 citation statements)

References 113 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…TAK , Takayasu arteritis; GCA , giant cell arteritis; PAN , polyarteritis nodosa; MPA , microscopic polyangiitis; EGPA , eosinophilic granulomatosis with polyangiitis; GPA , granulomatosis with polyangiitis; aGBM , antiglomerular basement membrane disease; Ig AV , IgA vasculitis; CV , cryoglobulinemic vasculitis; RV , rheumatoid vasculitis. Revised from reference 3. Kawasaki disease is excluded in this diagnostic procedure because the diagnostic procedure for Kawasaki disease is based solely on characteristic clinical signs and symptoms…”

Section: Concept Of Vasculitis Syndrome For Diagnosismentioning

confidence: 99%

“…PSL , prednisolone; MTX , methotrexate; PO , oral administration; IV , intravenous injection; CsA, cyclosporin A; AZP , azathioprine; MMF , mycophenolate mofetil. Revised from reference 3 …”

Section: Treatment Of Vasculitismentioning

confidence: 99%

“…Revised from reference 3. mPSL, methylprednisolone; PSL, prednisolone; IVCY, intravenous cyclophosphamide; CY, cyclophosphamide…”

Section: Treatment Of Vasculitismentioning

confidence: 99%

See 2 more Smart Citations

Vasculitis syndrome—diagnosis and therapy

Okazaki

Shinagawa

Mikage

2017

J of Gen and Family Med

View full text Add to dashboard Cite

In patients with connective tissue disease, vascular injury induced by primary or secondary vasculitis syndromes can lead to organ dysfunction due to the loss of nutrient supply from the blood. Such vasculitis syndromes can be refractory to treatment and fatal. The nomenclature and the definition of vasculitis syndromes have recently been revised, and clinical practice guidelines for diseases associated with vasculitis syndrome are evolving. The present review provides an overview of vasculitis syndromes from the viewpoint of diagnosis and treatment.

show abstract

Section: Concept Of Vasculitis Syndrome For Diagnosismentioning

confidence: 99%

Section: Treatment Of Vasculitismentioning

confidence: 99%

See 1 more Smart Citation

Vasculitis syndrome—diagnosis and therapy

Okazaki

Shinagawa

Mikage

2017

J of Gen and Family Med

View full text Add to dashboard Cite

show abstract

“…Ultrasound may thus be the first imaging approach in such patients. FDG-PET, especially if combined with anatomical CT imaging, appears to be particularly appropriate subsequently, as it allows to detect lesions throughout the entire arterial tree (128). PET imaging may be particularly appropriate for patients affected by GCA (127) in whom large-vessel involvement and systemic symptoms, e.g., limb claudication, predominate, and in patients with atypical presentation, i.e., fever of unknown origin (122).…”

Section: Conclusive Clinical Remarksmentioning

confidence: 99%

Non-Invasive Imaging of Vascular Inflammation

et al. 2014

View full text Add to dashboard Cite

In large-vessel vasculitides, inflammatory infiltrates may cause thickening of the involved arterial vessel wall leading to progressive stenosis and occlusion. Dilatation, aneurysm formation, and thrombosis may also ensue. Activated macrophages and T lymphocytes are fundamental elements in vascular inflammation. The amount and density of the inflammatory infiltrate is directly linked to local disease activity. Additionally, patients with autoimmune disorders have an increased cardiovascular (CV) risk compared with age-matched healthy individuals as a consequence of accelerated atherosclerosis. Molecular imaging techniques targeting activated macrophages, neovascularization, or increased cellular metabolic activity can represent effective means of non-invasive detection of vascular inflammation. In the present review, novel non-invasive imaging tools that have been successfully tested in humans will be presented. These include contrast-enhanced ultrasonography, which allows detection of neovessels within the wall of inflamed arteries; contrast-enhanced CV magnetic resonance that can detect increased thickness of the arterial wall, usually associated with edema, or mural enhancement using T2 and post-contrast T1-weighted sequences, respectively; and positron emission tomography associated with radio-tracers such as [18F]-fluorodeoxyglucose and the new [11C]-PK11195 in combination with computed tomography angiography to detect activated macrophages within the vessel wall. Imaging techniques are useful in the diagnostic work-up of large- and medium-vessel vasculitides, to monitor disease activity and the response to treatments. Finally, molecular imaging targets can provide new clues about the pathogenesis and evolution of immune-mediated disorders involving arterial vessels.

show abstract

“…Women are affected in 80 to 90 percent of cases, typically before the age of 40 years [1] . In Japan, more than 5,000 cases are registered by the government and the number of patients increases by 200 to 400 every 3 years [2] . A positive association with HLA-B52 and HLA-B39 has been demonstrated in several studies, suggesting an immunogenic association [3] .…”

Section: Introductionmentioning

confidence: 99%

A case of atypical Takayasu arteritis initially presenting with peripheral artery disease

Kawano

Hashimoto

Yoshijima

et al. 2014

CRCP

View full text Add to dashboard Cite

A 28-year-old woman developed Raynaud's phenomenon and sudden left visual loss due to hypertensive retinopathy. One and a half years later, she noticed peripheral coldness and numbness of right foot. Enhanced computed tomography showed remarkable stenosis of left radial and bilateral tibial arteries. Initially, the diagnosis of idiopathic peripheral arterial occlusive disease (PAD) was made. PAD gradually progressed despite the medication with antiplatelet drug and vasodilator, and coronary angiography revealed a left coronary artery aneurysm. Then, she developed the same ischemic symptom of right hand and left visual loss caused by papilledema. Although 18 F-fluorodeoxyglucose positron-emission tomography showed no abnormalities, and both HLA-B52 and HLA-B39 were negative, she was diagnosed with atypical Takayasu arteritis (TA) by exclusion of other possible diseases. To the best of our knowledge, this is the first case of TA with coronary aneurysm and PAD. In TA patients, the involvement of medium-sized vascular lesion such as peripheral extremity arteries should be considered.

show abstract

Guideline for Management of Vasculitis Syndrome (JCS 2008) - Digest Version -

Cited by 145 publications

References 113 publications

Vasculitis syndrome—diagnosis and therapy

Vasculitis syndrome—diagnosis and therapy

Non-Invasive Imaging of Vascular Inflammation

A case of atypical Takayasu arteritis initially presenting with peripheral artery disease

Contact Info

Product

Resources

About