Growth rate of non-operated meningiomas

Abstract

The mean volumetric growth rate was significantly greater than the planimetric growth rate, suggesting that volumetric measurement conveys more information and is superior in assessing tumor growth. This information could have clinical value in determining the frequency of follow-up imaging and the urgency of surgical intervention.

Reliability of the Size Evaluation Method for Meningiomas: Maximum Diameter, ABC/2 Formula, and Planimetry Method

“…The planimetry method has been widely used to calculate the volume of meningiomas in previous studies (3,4,(11)(12)(13)(14)(15); however, the details of the procedure depend on each investigator. The thickness of MRI used in the planimetry method is often not regarded in the study.…”

“…Although some studies have used the ABC/2 formula (2,25,26) or the original ellipsoid volume (10,19,27) to measure the volume of intracranial tumors, including meningiomas, few studies have evaluated the accuracy of ABC/2 formula for intracranial tumors. The planimetry method presents a more approximate volume for the real tumor and has been applied in many studies (3,4,(11)(12)(13)(14)(15); however, this method is more cumbersome than the ABC/2 method. In addition, the thickness of MRI used to calculate tumor volume differs between each investigator.…”

The Natural Course of Incidental Intracranial Meningiomas: Systematic Review and Meta-Analysis.

“…Thirteen studies measured various aspects of the growth rate [3,4,5,6,7,10,11,14,17,19,21,22,23] (Table 4). Six measured growth rate in diameter.…”

“…Zeidman et al found a 3.82% per year difference between relative growth in planimetric versus volumetric measures with a p<0.0001. [23] Ten out of the twenty studies utilized planimetric measurements of initial size of tumor while eight studies used volumetric measures. Niiro et al found a significant different in initial size in diameter between growing and nongrowing tumors reporting a p-value of 0.016 [13].…”

“…Published reports are often limited by a retrospective study design, small sample size, and short follow-up period. [1][2][3][4][5][6][7][8][9][10][11][12][13][14]16,17,19,[21][22][23] A systematic review and meta-analysis of the studies currently available allows for a better understanding of the natural course of asymptomatic meningiomas, a platform for more research, and a foundation on which a standardized guideline for following these tumors may be built.…”