Growth potential of the rat clavicle

Clavicle in Carnivorans: A Forgotten Bone

“…According to Černý and Čižinauskas (), the intraspecific variation in clavicles shape results from the reduction the bone undergoes during fetal development. In humans, mice, and rats, the clavicle is one of the first bones to go through ossification during pregnancy (Tran and Hall, ; Ronning et al, ). Clavicle ossification in domestic cats occurs late, only after halfway through the gestation (53%), when its development is inhibited (Rojas and Montenegro, ).…”

Clavicle in Carnivorans: A Forgotten Bone

“…According to Černý and Čižinauskas (), the intraspecific variation in clavicles shape results from the reduction the bone undergoes during fetal development. In humans, mice, and rats, the clavicle is one of the first bones to go through ossification during pregnancy (Tran and Hall, ; Ronning et al, ). Clavicle ossification in domestic cats occurs late, only after halfway through the gestation (53%), when its development is inhibited (Rojas and Montenegro, ).…”

Potential conversion of adult clavicle‐derived chondrocytes into neural lineage cells in vitro

“…In the present study we chose the clavicle bone to isolate cartilage as it is the only bone that does not have marrow (Hall, 2005c) so that a possible marrow contamination is further eliminated. In addition, as the only dermal skeletal elements in the trunk, and the first bone to ossify in rodents, the medial part cartilage of clavicle bone consists of actively dividing cartilaginous cells, histologically resembling with the condylar cartilage of the mandible (Ronning and Kantomaa, 1988;Ronning et al, 1991;Rintala et al, 1996;Hall, 2005c) are likely derivatives of neural crest (Graham et al, 2004;Matsuoka et al, 2005;Hall, 2005c). Another distinct feature of chondrocytes is their phenotypic instability in vitro as chondrocytes have a propensity to de-differentiate into a fibroblast-like phenotype (Schnabel et al, 2002;Vats et al, 2005) and their de-differentiation or trans-differentiation may occur easier than other adult committed cells.…”

Dislodged caval stent in right pulmonary artery

“…In the present study we chose the clavicle bone to isolate cartilage as it is the only bone that does not have marrow (Hall, 2005c) so that a possible marrow contamination is further eliminated. In addition, as the only dermal skeletal elements in the trunk, and the first bone to ossify in rodents, the medial part cartilage of clavicle bone consists of actively dividing cartilaginous cells, histologically resembling with the condylar cartilage of the mandible (Ronning and Kantomaa, 1988; Ronning et al, 1991; Rintala et al, 1996; Hall, 2005c) are likely derivatives of neural crest (Graham et al, 2004; Matsuoka et al, 2005; Hall, 2005c). Another distinct feature of chondrocytes is their phenotypic instability in vitro as chondrocytes have a propensity to de‐differentiate into a fibroblast‐like phenotype (Schnabel et al, 2002; Vats et al, 2005) and their de‐differentiation or trans‐differentiation may occur easier than other adult committed cells.…”

Clavicle in Carnivorans: A Forgotten Bone

“…According to Černý and Čižinauskas (), the intraspecific variation in clavicles shape results from the reduction the bone undergoes during fetal development. In humans, mice, and rats, the clavicle is one of the first bones to go through ossification during pregnancy (Tran and Hall, ; Ronning et al, ). Clavicle ossification in domestic cats occurs late, only after halfway through the gestation (53%), when its development is inhibited (Rojas and Montenegro, ).…”

Potential conversion of adult clavicle‐derived chondrocytes into neural lineage cells in vitro

“…In the present study we chose the clavicle bone to isolate cartilage as it is the only bone that does not have marrow (Hall, 2005c) so that a possible marrow contamination is further eliminated. In addition, as the only dermal skeletal elements in the trunk, and the first bone to ossify in rodents, the medial part cartilage of clavicle bone consists of actively dividing cartilaginous cells, histologically resembling with the condylar cartilage of the mandible (Ronning and Kantomaa, 1988;Ronning et al, 1991;Rintala et al, 1996;Hall, 2005c) are likely derivatives of neural crest (Graham et al, 2004;Matsuoka et al, 2005;Hall, 2005c). Another distinct feature of chondrocytes is their phenotypic instability in vitro as chondrocytes have a propensity to de-differentiate into a fibroblast-like phenotype (Schnabel et al, 2002;Vats et al, 2005) and their de-differentiation or trans-differentiation may occur easier than other adult committed cells.…”

Dislodged caval stent in right pulmonary artery

“…In the present study we chose the clavicle bone to isolate cartilage as it is the only bone that does not have marrow (Hall, 2005c) so that a possible marrow contamination is further eliminated. In addition, as the only dermal skeletal elements in the trunk, and the first bone to ossify in rodents, the medial part cartilage of clavicle bone consists of actively dividing cartilaginous cells, histologically resembling with the condylar cartilage of the mandible (Ronning and Kantomaa, 1988; Ronning et al, 1991; Rintala et al, 1996; Hall, 2005c) are likely derivatives of neural crest (Graham et al, 2004; Matsuoka et al, 2005; Hall, 2005c). Another distinct feature of chondrocytes is their phenotypic instability in vitro as chondrocytes have a propensity to de‐differentiate into a fibroblast‐like phenotype (Schnabel et al, 2002; Vats et al, 2005) and their de‐differentiation or trans‐differentiation may occur easier than other adult committed cells.…”

Clavicle in Carnivorans: A Forgotten Bone

“…According to Černý and Čižinauskas (), the intraspecific variation in clavicles shape results from the reduction the bone undergoes during fetal development. In humans, mice, and rats, the clavicle is one of the first bones to go through ossification during pregnancy (Tran and Hall, ; Ronning et al, ). Clavicle ossification in domestic cats occurs late, only after halfway through the gestation (53%), when its development is inhibited (Rojas and Montenegro, ).…”

Potential conversion of adult clavicle‐derived chondrocytes into neural lineage cells in vitro

“…In the present study we chose the clavicle bone to isolate cartilage as it is the only bone that does not have marrow (Hall, 2005c) so that a possible marrow contamination is further eliminated. In addition, as the only dermal skeletal elements in the trunk, and the first bone to ossify in rodents, the medial part cartilage of clavicle bone consists of actively dividing cartilaginous cells, histologically resembling with the condylar cartilage of the mandible (Ronning and Kantomaa, 1988;Ronning et al, 1991;Rintala et al, 1996;Hall, 2005c) are likely derivatives of neural crest (Graham et al, 2004;Matsuoka et al, 2005;Hall, 2005c). Another distinct feature of chondrocytes is their phenotypic instability in vitro as chondrocytes have a propensity to de-differentiate into a fibroblast-like phenotype (Schnabel et al, 2002;Vats et al, 2005) and their de-differentiation or trans-differentiation may occur easier than other adult committed cells.…”

Dislodged caval stent in right pulmonary artery

“…In the present study we chose the clavicle bone to isolate cartilage as it is the only bone that does not have marrow (Hall, 2005c) so that a possible marrow contamination is further eliminated. In addition, as the only dermal skeletal elements in the trunk, and the first bone to ossify in rodents, the medial part cartilage of clavicle bone consists of actively dividing cartilaginous cells, histologically resembling with the condylar cartilage of the mandible (Ronning and Kantomaa, 1988; Ronning et al, 1991; Rintala et al, 1996; Hall, 2005c) are likely derivatives of neural crest (Graham et al, 2004; Matsuoka et al, 2005; Hall, 2005c). Another distinct feature of chondrocytes is their phenotypic instability in vitro as chondrocytes have a propensity to de‐differentiate into a fibroblast‐like phenotype (Schnabel et al, 2002; Vats et al, 2005) and their de‐differentiation or trans‐differentiation may occur easier than other adult committed cells.…”