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Cited by 60 publications
(63 citation statements)
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“…15 An autopsy study has shown that the growth of the normal optic disc and nerve is 50% complete at 20 weeks of gestation, 75% complete at birth, and 95% complete before 1 year. 16 This is also in accordance with the findings of other studies that showed an absence of increase in optic disc area with age in a group of healthy children aged between 2 and 10 years. 17 The full-term infant spends the last months of gestation in the relatively stable environment of the uterus, whereas the premature infant spends the corresponding time period in a markedly different environment, with altered functional and metabolic requirements.…”
Section: Discussionsupporting
confidence: 93%
“…15 An autopsy study has shown that the growth of the normal optic disc and nerve is 50% complete at 20 weeks of gestation, 75% complete at birth, and 95% complete before 1 year. 16 This is also in accordance with the findings of other studies that showed an absence of increase in optic disc area with age in a group of healthy children aged between 2 and 10 years. 17 The full-term infant spends the last months of gestation in the relatively stable environment of the uterus, whereas the premature infant spends the corresponding time period in a markedly different environment, with altered functional and metabolic requirements.…”
Section: Discussionsupporting
confidence: 93%
“…The present study was performed at an age when continued growth of the optic nerve is unlikely as histologic and clinical studies have shown that there is no measurable growth of the optic nerve after 3 y of age (15,16). The observed reduction in axonal area in subjects with IUGR may reflect either reduced axonal growth with a reduction of axonal volume or a decrease in the number of axons, i.e., in the number of neurons.…”
Section: Discussionmentioning
confidence: 90%
“…3 In children born at a gestational age (GA) of less than 29 weeks the development of the optic nerve is far from complete, as only 75% of the growth is achieved even after 40 weeks of gestation. 4 It was suggested that preterm birth may be associated with an increased risk of optic nerve hypoplasia. Damage to the optic nerve in children born prematurely might occur prenatally and be caused by factors responsible for the preterm birth, or it may occur peri-or postnatally by morbidity associated with immaturity.…”
Section: Ann Hellstro M Anna-lena Hard Elisabeth Svensson Almon Nimentioning
confidence: 99%