Group contributions to hydrophobicity and elution behaviour of pyridine derivatives in reversed-phase high-performance liquid chromatography

Evaluation of mixed-mode stationary phases in liquid chromatography for the separation of charged and uncharged oligomer-like model compounds

“…The columns did not show a poor performance for basic compounds, in comparison with silica-based reversed-phase columns. This is a result of the lack of interfering interactions by the basic pyridines with the free silanol groups present on silica surfaces [32]. The hydrophobicity of the columns increases in the range PLl, PL2, PRP-X100 and OmniPac PAX-500, taking the percentage of organic modifier necessary to elute the alkylbenzenes from a column into account.…”

Evaluation of mixed-mode stationary phases in liquid chromatography for the separation of charged and uncharged oligomer-like model compounds

“…The columns did not show a poor performance for basic compounds, in comparison with silica-based reversed-phase columns. This is a result of the lack of interfering interactions by the basic pyridines with the free silanol groups present on silica surfaces [32]. The hydrophobicity of the columns increases in the range PLl, PL2, PRP-X100 and OmniPac PAX-500, taking the percentage of organic modifier necessary to elute the alkylbenzenes from a column into account.…”

Evaluation of mixed-mode stationary phases in liquid chromatography for the separation of charged and uncharged oligomer-like model compounds

“…The columns did not show a poor performance for basic compounds, in comparison with silica-based reversed-phase columns. This is a result of the lack of interfering interactions by the basic pyridines with the free silanol groups present on silica surfaces [32]. The hydrophobicity of the columns increases in the range PLl, PL2, PRP-X100 and OmniPac PAX-500, taking the percentage of organic modifier necessary to elute the alkylbenzenes from a column into account.…”

Evaluation of mixed-mode stationary phases in liquid chromatography for the separation of charged and uncharged oligomer-like model compounds

“…The columns did not show a poor performance for basic compounds, in comparison with silica-based reversed-phase columns. This is a result of the lack of interfering interactions by the basic pyridines with the free silanol groups present on silica surfaces [32]. The hydrophobicity of the columns increases in the range PLl, PL2, PRP-X100 and OmniPac PAX-500, taking the percentage of organic modifier necessary to elute the alkylbenzenes from a column into account.…”