Green tea catechins and broccoli reduce fat-induced mortality in Drosophila melanogaster

Li, Yuk Man; Chan, Ho Yin Edwin; Yao, Xiaoqiang; Huang, Yü; Chen, Zhen Yu

doi:10.1016/j.jnutbio.2007.05.009

Cited by 49 publications

(35 citation statements)

References 36 publications

(42 reference statements)

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“…Although the flavonoid content of this powder had not been analysed as part of the study, we included it because cocoa powder is known to have high flavonoid content (68) . Bahdorani Li et al (69) Literature review of flavonoids and lifespan in model organisms (66) EGCG, epigallocatechin gallate; CSY, cornmeal-sugar-yeast. * If the numbers in the control and treatment groups are different, the lower number is given.…”

Section: Flavonoids and The Lifespan Of Drosophila Melanogastermentioning

confidence: 99%

A literature review of flavonoids and lifespan in model organisms

Pallauf¹,

Duckstein²,

Rimbach³

2016

Proc. Nutr. Soc.

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Epidemiological data on consumption of flavonoid-containing food points to the notion that some of these secondary plant metabolites may favour healthy ageing. The aim of the present paper was to review the literature on lifespan extension by flavonoids in worms, flies and mice. In most studies, worms and flies experienced lifespan extension when supplemented with flavonoids either as extracts or single compounds. Studies with mutant worms and flies give hints as to which gene products may be regulated by flavonoids and consequently enhance longevity. We discuss the data considering putative mechanisms that may underlie flavonoid action such as energy-restriction-like effects, inhibition of insulin-like-growth-factor signalling, induction of antioxidant defence mechanisms, hormesis as well as antimicrobial properties. However, it remains uncertain whether human lifespan could be prolonged by increased flavonoid intake.

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Section: Flavonoids and The Lifespan Of Drosophila Melanogastermentioning

confidence: 99%

A literature review of flavonoids and lifespan in model organisms

Pallauf¹,

Duckstein²,

Rimbach³

2016

Proc. Nutr. Soc.

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“…The standard diet was prepared according to the previously reported formula (Li et al, 2008;Wang et al, 2015). In brief, 1000 mL of diet contained 105 g cornmeal, 105 g glucose, 21 g yeast and 13 g agar.…”

Section: Fly Strain and Dietsmentioning

confidence: 99%

“…Increasing evidence has demonstrated that consumption of vegetables and fruits could promote health, prevent and delay age-related diseases. In this regard, some phytochemicals derived from vegetables and fruits have been shown to improve the survival rate of mice or fruit flies fed a high-fat diet (Baur et al, 2006;Boyd et al, 2011;Li et al, 2008;Sun et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster

Wang

Lei

et al. 2016

Experimental Gerontology

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“…A number of studies in the recent past have shown the beneficial effects of nutraceuticals-secondary compounds produced by plants in promoting healthy aging in invertebrate models through reduced oxidative damage (Dong et al 2012). Aloe vera (Chandrashekara and Shakarad 2011), blueberry (Peng et al 2012), and green tea (Li et al 2007(Li et al , 2008 extract supplementation of fly diet increased the lifespan through increased activity of antioxidant enzymes-superoxide dismutase and catalase. Spermidine supplementation of ordinary fly food increased the mean lifespan of flies up to 30 % (Eisenberg et al 2009).…”

Section: Drmentioning

confidence: 99%

Curcumin enhances parental reproductive lifespan and progeny viability in Drosophila melanogaster

Chandrashekara

Popli

Shakarad

2014

AGE

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Organismal lifespan is a complex trait that is governed by both its genetic makeup as well as the environmental conditions. The improved socioeconomic condition of humans has led to many lifestyle changes that in turn have altered the demography that includes postponement of procreation. Late age progeny is shown to suffer from many congenital diseases. Hence, there is a need to identify and evaluate natural molecules that could enhance reproductive health span. We have used the well-established model organism, Drosophila melanogaster, and ascertained the consequence of diet supplementation with curcumin. Flies reared on curcumin-supplemented diet had significantly higher lifespan. The progeny of flies reared on curcumin had a higher viability. The activity of a key mitochondrial enzyme-aconitase was significantly higher in flies reared on curcumin-supplemented diet. The results suggest that curcumin can not only correct a key step in the citric acid cycle and help in the release of additional energy but also permanently correct developmental and morphogenetic processes.

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Green tea catechins and broccoli reduce fat-induced mortality in Drosophila melanogaster

Cited by 49 publications

References 36 publications

A literature review of flavonoids and lifespan in model organisms

A literature review of flavonoids and lifespan in model organisms

Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster

Curcumin enhances parental reproductive lifespan and progeny viability in Drosophila melanogaster

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