We study null 1/4 BPS deformations of flat Domain Wall solutions (NDDW) in N = 2, d = 5 gauged supergravity with hypermultiplets and vector multiplets coupled. These are uncharged timedependent configurations and contain as special case, 1/2 supersymmetric flat domain walls (DW) and, as well, 1/2 BPS null solutions of the ungauged supergravity. Combining our analysis with the classification method initiated by Gauntlett et al., we prove that all the possible deformations of the DW have origin in the hypermultiplet sector or/and are null. Here, we classify all the null deformations: we show that they naturally organize in "gauging" (v-deformation) and "non gauging" (u-deformation). They have different properties: only in presence of v-deformation the solution is supported by a timedependent scalar potential. Furthermore we show that u-deformation forces the number of multiplets coupled to be different by one. We discuss the general procedure for constructing explicit solutions, stressing the crucial role taken by the integrability conditions of the scalars as spacetime functions. Two analytical solutions are presented. Finally, we comment on the holographic applications of NDDW, in relation with the recently proposed timedependent AdS/CFT.