Graphenic substrates as modifiers of the emission and vibrational responses of interacting molecules: The case of BODIPY dyes

Modulating the interaction of graphenic substrates with human interleukin-6 and its monoclonal antibody: a study by Raman images

“…These interactions would be responsible, through a charge transfer mechanism, for an increase of the adsorbed molecule polarizability which promotes the amplication of their Raman signals. 19,21,22 In this sense, in a previous publication of our group 19 we showed that the detection limits of IL-6 deposited on rGO substrates, was better than 1 pg mL −1 , corresponding with an absolute mass as low as 1 fg.…”

“…19,20 GERS spectroscopy is based on the use of graphenic substrates (GS) such as pristine graphene (G), graphene oxide (GO) or reduced graphene oxide (rGO) as Raman signal enhancement substrates. 19,21,22 Graphene oxide-type substrates can interact, through their basal plane aromatic domain and/or their edge-located oxygenated polar species, with aromatic or polar molecules giving rise to rich and complex association processes between them. These interactions would be responsible, through a charge transfer mechanism, for an increase of the adsorbed molecule polarizability which promotes the amplication of their Raman signals.…”

“…This fact leads to a more reliable and reproducible identication of their vibrational modes. 19,21 Moreover, the physicochemical properties of graphene materials can be modied by changing the oxygenated groups in their basal plane and at their edge, or by controlling the arrangement and thickness of the thin lms of graphenic substrates (GS) on multilayers supports. The possibility to adjust their physicochemical properties allows the promotion of a great variety of specic interactions (electrostatic, hydrogen bridges, p-p, hydrophobic) with different biomolecules and metabolites, such as hemoglobin, 23 albumin, 23 human interleukin-6, 19 5-S-cysteinyl-dopamine, 24 DNA, 25 among others, which makes GS attractive and versatile materials for the development of highly specic and sensitive biosensors.…”

Carbon SH-SAW-Based Electronic Nose to Discriminate and Classify Sub-ppm NO2

“…Particle distribution is identified with particle sizes below 100 nm and pores in the order of 100–200 nm. Figure 2 b shows the GO layer, where there is deposition of completely extended sheets favored by the LB technique, showing a flat surface with wrinkles, edges and some particular bumped features of 300 nm in diameter [ 42 ]. On the other hand, Figure 2 b,d shows the sensitive layers based on rGO and PDA/rGO, respectively.…”

Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy for Probing Riboflavin on Graphene

“…Nevertheless, resonance Raman spectroscopy provides information on the structure of graphene skeleton [ 12 ]; usually, no direct information on the structure of molecular groups covalently attached to the carbon matrix or adsorbed compounds can be acquired. In some cases, adsorbed organic molecules can be probed by graphene-enhanced Raman spectroscopy (GERS) [ 15 , 16 , 17 , 18 , 19 , 20 , 21 ]. In GERS the dominant Raman signal enhancement mechanism is chemical enhancement due to charge transfer excitation [ 17 , 21 ].…”