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Granulomatous Sclerouveitis
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Cited by 58 publications
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Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Cyclophosphamide has been effective in treating scleritis caused by underlying systemic disorders such as granulomatosis with polyangiitis (GPA), rheumatoid arthritis, polyarteritis nodosa and relapsing polychondritis [ 23 – 26 ]. In the SITE cohort study, 215 patients receiving cyclophosphamide for ocular inflammation were studied and 76% of them achieved inflammation control at 1 year.…”
Section: Discussion
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Cyclophosphamide has been effective in treating scleritis caused by underlying systemic disorders such as granulomatosis with polyangiitis (GPA), rheumatoid arthritis, polyarteritis nodosa and relapsing polychondritis [ 23 – 26 ]. In the SITE cohort study, 215 patients receiving cyclophosphamide for ocular inflammation were studied and 76% of them achieved inflammation control at 1 year.…”
Section: Discussion
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…In adults, cyclophosphamide in addition to corticosteroids is useful in the treatment of Wegener's granulomatosis and peripheral ulcerative keratitis. 133,134 Medication-induced azoospermia or damage to the ovaries may necessitate sperm banking and harvesting of ova in teenagers and adults. The side effect of leukopenia requires constant monitoring of the blood cell count and the risk of secondary malignancy and chromosomal damage, although uncommon, can be problematic.…”
Section: Clinical Management
mentioning
confidence: 99%
“…Alkylating agents such as cyclophosphamide (Cytoxan; Bristol-Myers Squibb, New York, NY), chlorambucil (Leukeran; GlaxoSmithKline, Brentford, UK), and the antimetabolite azathioprine (Imuran; GlaxoSmithKline) are not commonly used in childhood or adult uveitis due to their side effects. In adults, cyclophosphamide in addition to corticosteroids is useful in the treatment of Wegener's granulomatosis and peripheral ulcerative keratitis 133,134. Medication-induced azoospermia or damage to the ovaries may necessitate sperm banking and harvesting of ova in teenagers and adults.…”
Section: Clinical Management
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Cyclophosphamide has been effective in treating scleritis caused by underlying systemic disorders such as granulomatosis with polyangiitis (GPA), rheumatoid arthritis, polyarteritis nodosa and relapsing polychondritis [ 23 – 26 ]. In the SITE cohort study, 215 patients receiving cyclophosphamide for ocular inflammation were studied and 76% of them achieved inflammation control at 1 year.…”
Section: Discussion
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…In adults, cyclophosphamide in addition to corticosteroids is useful in the treatment of Wegener's granulomatosis and peripheral ulcerative keratitis. 133,134 Medication-induced azoospermia or damage to the ovaries may necessitate sperm banking and harvesting of ova in teenagers and adults. The side effect of leukopenia requires constant monitoring of the blood cell count and the risk of secondary malignancy and chromosomal damage, although uncommon, can be problematic.…”
Section: Clinical Management
mentioning
confidence: 99%
“…Alkylating agents such as cyclophosphamide (Cytoxan; Bristol-Myers Squibb, New York, NY), chlorambucil (Leukeran; GlaxoSmithKline, Brentford, UK), and the antimetabolite azathioprine (Imuran; GlaxoSmithKline) are not commonly used in childhood or adult uveitis due to their side effects. In adults, cyclophosphamide in addition to corticosteroids is useful in the treatment of Wegener's granulomatosis and peripheral ulcerative keratitis 133,134. Medication-induced azoospermia or damage to the ovaries may necessitate sperm banking and harvesting of ova in teenagers and adults.…”
Section: Clinical Management
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Cyclophosphamide has been effective in treating scleritis caused by underlying systemic disorders such as granulomatosis with polyangiitis (GPA), rheumatoid arthritis, polyarteritis nodosa and relapsing polychondritis [ 23 – 26 ]. In the SITE cohort study, 215 patients receiving cyclophosphamide for ocular inflammation were studied and 76% of them achieved inflammation control at 1 year.…”
Section: Discussion
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…In adults, cyclophosphamide in addition to corticosteroids is useful in the treatment of Wegener's granulomatosis and peripheral ulcerative keratitis. 133,134 Medication-induced azoospermia or damage to the ovaries may necessitate sperm banking and harvesting of ova in teenagers and adults. The side effect of leukopenia requires constant monitoring of the blood cell count and the risk of secondary malignancy and chromosomal damage, although uncommon, can be problematic.…”
Section: Clinical Management
mentioning
confidence: 99%
“…Alkylating agents such as cyclophosphamide (Cytoxan; Bristol-Myers Squibb, New York, NY), chlorambucil (Leukeran; GlaxoSmithKline, Brentford, UK), and the antimetabolite azathioprine (Imuran; GlaxoSmithKline) are not commonly used in childhood or adult uveitis due to their side effects. In adults, cyclophosphamide in addition to corticosteroids is useful in the treatment of Wegener's granulomatosis and peripheral ulcerative keratitis 133,134. Medication-induced azoospermia or damage to the ovaries may necessitate sperm banking and harvesting of ova in teenagers and adults.…”
Section: Clinical Management
mentioning
confidence: 99%