Granulomatous Panniculitis Associated With Sjögren Syndrome

Chandrupatla, Chethana V.; Ling, Xinsheng; Stratman, Erik J.

doi:10.1001/archderm.144.6.815

Cited by 9 publications

(2 citation statements)

References 3 publications

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“…Moreover, only few cases of granulomatous panniculitis have reported to date. 3,6–8 In this context, the exclusion of other etiologies of panniculitis, such as erythema nodosum, mycobacterial infection, Crohn disease, and sarcoidosis, is crucial. 3,8…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, only few cases of granulomatous panniculitis have reported to date. 3,[6][7][8] In this context, the exclusion of other etiologies of panniculitis, such as erythema nodosum, mycobacterial infection, Crohn disease, and sarcoidosis, is crucial. 3,8 In addition, our patient had fever, a feature that occurs more frequently at disease onset, and it is usually accompanied by another extraglandular feature and frequently requires hospitalization.…”

Section: Discussionmentioning

confidence: 99%

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Granulomatous Panniculitis as an Initial Manifestation of Sjögren Syndrome

Méndez-Flores,

Méndez-Pérez,

Saeb-Lima

et al. 2024

The American Journal of Dermatopathology

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A 65-year-old woman presented with unexplained weight loss, recurrent fever, and a dermatosis with painful nodules on the extremities. Biopsies showed focal lobular panniculitis with neutrophilic microgranulomas. Comprehensive investigations ruled out infection and hematologic and solid organ neoplasms. Laboratory results showed anti-Ro/SSA and anti-La/SSB antibody positivity, and elevated inflammatory markers. Dry mouth and eye were confirmed. The diagnosis of Sjögren syndrome with cutaneous panniculitis was established. Prednisone treatment with 30 mg/d resulted in remission of fever and pain improvement. This case emphasizes Sjögren syndrome as an autoimmune disease with multiple cutaneous manifestations and highlights its association with granulomatous panniculitis.

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Section: Discussionmentioning

confidence: 99%